COVID-19 and Cardiovascular Disease From Bench to Bedside

被引：255

作者：

Chung, Mina K. ^{[1
,2
,3
]}

Zidar, David A. ^{[3
,4
]}

Bristow, Michael R. ^{[5
]}

Cameron, Scott J. ^{[1
,2
,3
]}

Chan, Timothy ^{[1
,2
,3
]}

Harding, Clifford V., III ^{[3
]}

Kwon, Deborah H. ^{[1
,2
,3
]}

Singh, Tamanna ^{[1
,2
,3
]}

Tilton, John C. ^{[3
]}

Tsai, Emily J. ^{[6
]}

Tucker, Nathan R. ^{[7
,8
]}

Barnard, John ^{[1
,2
]}

Loscalzo, Joseph ^{[9
]}

机构：

[1] Cleveland Clin, Cleveland, OH 44106 USA

[2] Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA

[3] Case Western Reserve Univ, Sch Med, Cleveland, OH 44106 USA

[4] Louis Stokes Cleveland Vet Affairs Med Ctr, Cleveland, OH USA

[5] Univ Colorado, Anschutz Med Ctr, Aurora, CO USA

[6] Columbia Univ, Vagelos Coll Phys & Surg, New York, NY USA

[7] Masonic Med Res Inst, Utica, NY USA

[8] Broad Inst Harvard & MIT, Cardiovasc Dis Initiat, Boston, MA USA

[9] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA

来源：

CIRCULATION RESEARCH | 2021年 / 128卷 / 08期

关键词：

angiotensin-converting enzyme 2; COVID-19; inflammation; magnetic resonance imaging; thrombosis; ANGIOTENSIN-CONVERTING ENZYME-2; CARDIAC MAGNETIC-RESONANCE; HUMAN CORONAVIRUS NL63; MYOCARDIAL INJURY; SPIKE PROTEIN; VIRUS ENTRY; HYPERTROPHIC CARDIOMYOPATHY; SARS CORONAVIRUS; PROGNOSTIC VALUE; UP-REGULATION;

D O I：

10.1161/CIRCRESAHA.121.317997

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can infect the heart, vascular tissues, and circulating cells through ACE2 (angiotensin-converting enzyme 2), the host cell receptor for the viral spike protein. Acute cardiac injury is a common extrapulmonary manifestation of COVID-19 with potential chronic consequences. This update provides a review of the clinical manifestations of cardiovascular involvement, potential direct SARS-CoV-2 and indirect immune response mechanisms impacting the cardiovascular system, and implications for the management of patients after recovery from acute COVID-19 infection.

引用

页码：1214 / 1236

页数：23

共 50 条

[1] COVID-19 and thrombosis: From bench to bedside
Ali, Mohammad A. M.
Spinler, Sarah A.
TRENDS IN CARDIOVASCULAR MEDICINE, 2021, 31 (03) : 143 - 160
[2] Bioengineering applied to Covid-19 pandemic: from bench to bedside
Buchaim, Rogerio Leone
AIMS BIOENGINEERING, 2021, 8 (01): : 14 - 15
[3] COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside
Sulzer, David
Antonini, Angelo
Leta, Valentina
Nordvig, Anna
Smeyne, Richard J.
Goldman, James E.
Al-Dalahmah, Osama
Zecca, Luigi
Sette, Alessandro
Bubacco, Luigi
Meucci, Olimpia
Moro, Elena
Harms, Ashley S.
Xu, Yaqian
Fahn, Stanley
Chaudhuri, K. Ray
NPJ PARKINSONS DISEASE, 2020, 6 (01)
[4] Recent Understandings Toward Coronavirus Disease 2019 (COVID-19): From Bench to Bedside
Yu, Jie
Chai, Peiwei
Ge, Shengfang
Fan, Xianqun
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
[5] COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside
David Sulzer
Angelo Antonini
Valentina Leta
Anna Nordvig
Richard J. Smeyne
James E. Goldman
Osama Al-Dalahmah
Luigi Zecca
Alessandro Sette
Luigi Bubacco
Olimpia Meucci
Elena Moro
Ashley S. Harms
Yaqian Xu
Stanley Fahn
K. Ray Chaudhuri
npj Parkinson's Disease, 6
[6] From bench to bedside: potential of translational research in COVID-19 and beyond
Shukla, Nityendra
Shamim, Uzma
Agarwal, Preeti
Pandey, Rajesh
Narayan, Jitendra
BRIEFINGS IN FUNCTIONAL GENOMICS, 2023, 23 (04) : 349 - 362
[7] "Three medicines and three formulas" in COVID-19: from bench to bedside
Xiao, Guangxu
Wang, Simeng
Wang, Ruijiao
Tan, Li
Ma, Shibo
He, Shuang
Fan, Guanwei
Zhu, Yan
Lyu, Ming
ACUPUNCTURE AND HERBAL MEDICINE, 2023, 3 (04) : 309 - 322
[8] Updates on bioengineering applied to Covid-19 pandemic: from bench to bedside
Buchaim, Rogerio Leone
AIMS BIOENGINEERING, 2023, 10 (01): : 24 - 26
[9] Mesenchymal Stem Cells in COVID-19: A Journey from Bench to Bedside
Sahu, Kamal Kant
Siddiqui, Ahmad Daniyal
Cerny, Jan
LABORATORY MEDICINE, 2021, 52 (01) : 24 - 35
[10] Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside
Abadi, Banafshe
Jeshvaghani, Amir Hossein Aarabi
Fathalipour, Hadis
Dehghan, Leili
Sirjani, Kosar Rahimi
Forootanfar, Hamid
IRANIAN JOURNAL OF MEDICAL SCIENCES, 2022, 47 (06) : 517 - 532

← 1 2 3 4 5 →