Novel series of 8H-quinazolino[4,3-b]quinazolin-8-ones via two Niementowski condensations

被引：88
作者：
Alexandre, FR
Berecibar, A
Wrigglesworth, R
Besson, T
机构：
[1] Univ La Rochelle, Lab Genie Prot & Cellulaire, EA 3169, Grp Chim Organ,UFR Sci Fondamentales & Sci Ingn, F-17042 La Rochelle 1, France
[2] Pfizer Global Res & Dev, Fresnes Labs, F-94265 Fresnes, France
来源：
TETRAHEDRON | 2003年 / 59卷 / 09期
关键词：
nitrogen heterocycles; fused ring systems; microwave-assisted multi-steps synthesis; cyclisation;
D O I：
10.1016/S0040-4020(03)00053-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Efficient microwave-assisted multi-step synthesis of 8H-quinazolino[4,3-b]quinazolin-8-one was investigated. The synthesis involved two Niementowski condensations from anthranilic acids. Homogeneous or heterogeneous conditions were studied with the aim to develop convenient syntheses of the desired compounds. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1413 / 1419
页数：7
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