Spontaneous regression of osteochondromas

Spontaneous regression of an osteochondroma is an infrequent event. In this report, two cases with spontaneous regression of osteochondromas are presented. The first case was a solitary osteochondroma of the pedunculated type involving the right proximal humerus in a 7-year-old boy. This lesion resolved over 15 months of observation. The second case was a 3-year-old girl with multiple osteochondromatosis, in whom sessile osteochondromas of the right tibia and left fibula regressed over 33 months.The mechanism of this phenomenon is discussed with a review of previous reports. Regarding treatment, careful observation may be acceptable for typical osteochondromas, especially in young children.