In order to research the flow behavior of 20CrMnTi and obtain its constitutive equation, the isothermal compression tests of 20CrMnTi were carried out using the Gleeble-3500 thermo-simulation machine, up to a 60% height reduction of the sample at strain rate range from 0.01 s(-1) to 10 s(-1) and deformation temperature range from 1123 K to 1273 K. According to the experimental results, the constitutive equation of 20CrMnTi was established based on Arrhenius model. In addition, the compensation of strain was taken into account and a new method of modifying the constitutive equation was proposed by introducing a coefficient K related to the deformation temperature and stain rate, which effectively improved the prediction accuracy of the developed constitutive equation. The results show that the flow stress decreases with increasing deformation temperature and decreasing strain rate, and the proposed constitutive equation well predicts the flow stress of 20CrMnTi during the high temperature deformation.