Immune response to SARSCoV-2 infection and vaccination in patients receiving kidney replacement therapy

被引:63
作者
Ikizler, T. Alp [1 ]
Coates, P. Toby [2 ]
Rovin, Brad H. [3 ]
Ronco, Pierre [4 ,5 ,6 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Med, Div Nephrol & Hypertens, Nashville, TN USA
[2] Univ Adelaide, Ctr Clin & Expt Transplantat, Adelaide, SA, Australia
[3] Ohio State Univ, Wexner Med Ctr, Internal Med Nephrol, Columbus, OH 43210 USA
[4] Univ Pierre & Marie Curie Paris 06, Sorbonne Univ, UMR S 1155, Paris, France
[5] Inst Natl Sante & Rech Med, Paris, France
[6] Ctr Hosp Mans, Div Nephrol, Le Mans, France
关键词
CALL;
D O I
10.1016/j.kint.2021.04.007
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
In this issue of Kidney International, the initial experience regarding the immunogenicity of prior coronavirus disease 2019 (COVID-19) infection and the response to the COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients is summarized. Preliminary data suggest that there is durability of immune response after COVID-19 infection. Although immune response to the first dose of vaccine is less in infection-naive patients than healthy individuals in both groups, after the second vaccine dose a significant portion of patients receiving maintenance dialysis develop robust antibody titers, whereas kidney transplant recipients show a less-strong immune response.
引用
收藏
页码:1275 / 1279
页数:5
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