Intravascular ultrasound assessment of neointima distribution and the length of stent that was free of intravascular ultrasound-detectable intimal hyperplasia in paclitaxel-eluting stents

被引：16

作者：

Mintz, GS

Hong, MK

Raizner, AE

Lee, CW

Kim, JJ

Escolar, E

Fearnot, NE

Park, SW

Park, SJ

Weissman, NJ

机构：

[1] Washington Hosp Ctr, Washington, DC 20010 USA

[2] Univ Ulsan, Coll Med, Dept Med, Seoul, South Korea

[3] Cardiovasc Res Fdn, New York, NY USA

[4] MED Inst Inc, W Lafayette, IN USA

[5] Methodist DeBakey Heart Ctr, Cardiovasc Angiog Anal Lab, Houston, TX USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2005年 / 95卷 / 01期

关键词：

D O I：

10.1016/j.amjcard.2004.08.072

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Using data from the ASian Paclitaxel-Eluting Stent Clinical Trial, a 3-center, randomized, placebo-controlled trial of nonpolymeric paclitaxel-coated stents with a single center, 81-patient intravascular ultrasound (IVUS) substudy, the length of a stent that was free of IVUS-detectable intimal hyperplasia measured 3.2 +/- 4.8 mm in placebo stents, 6.1 +/- 5.6 mm in low-dose stents, and 8.7 +/- 6.1 mm in high-dose stents (p = 0.0029). IVUS percent neointima volume obstruction con-elated with the length of this IVUS neointima-free segment (r = 0.785, p < 0.0001); angiographic late lumen loss and follow-up diameter stenosis also correlated with the IVUS neointima-free length of the stents (r = 0.670, p < 0.0001 and r = 0.679, p < 0.0001, respectively. (C) 2005 by Excerpta Medica Inc.

引用

页码：107 / 109

页数：3

共 11 条

[1] Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesions [J].

Colombo, A ;

Drzewiecki, J ;

Banning, A ;

Grube, E ;

Hauptmann, K ;

Silber, S ;

Dudek, D ;

Fort, S ;

Schiele, F ;

Zmudka, K ;

Guagliumi, G ;

Russell, ME .

CIRCULATION, 2003, 108 (07) :788-794

[2] Long-term follow-up of incomplete stent apposition in patients who received sirolimus-eluting stent for de novo coronary lesions - An intravascular ultrasound analysis [J].

Degertekin, M ;

Serruys, PW ;

Tanabe, K ;

Lee, CH ;

Sousa, JE ;

Colombo, A ;

Morice, MC ;

Ligthart, JMR ;

de Feyter, PJ .

CIRCULATION, 2003, 108 (22) :2747-2750

[3] Patterns and mechanisms of in-stent restenosis - A serial intravascular ultrasound study [J].

Hoffmann, R ;

Mintz, GS ;

Dussaillant, GR ;

Popma, JJ ;

Pichard, AD ;

Satler, LF ;

Kent, KM ;

Griffin, J ;

Leon, MB .

CIRCULATION, 1996, 94 (06) :1247-1254

[4] Paclitaxel coating reduces in-stent intimal hyperplasia in human coronary arteries - A serial volumetric intravascular ultrasound analysis from the ASian paclitaxel-eluting stent clinical trial (ASPECT) [J].

Hong, MK ;

Mintz, GS ;

Lee, CW ;

Song, JM ;

Han, KH ;

Kang, DH ;

Song, JK ;

Kim, JJ ;

Weissman, NJ ;

Fearnot, NE ;

Park, SW ;

Park, SJ .

CIRCULATION, 2003, 107 (04) :517-520

[5] American College of Cardiology Clinical Expert Consensus Document on Standards for Acquisition, Measurement and Reporting of Intravascular Ultrasound Studies (IVUS) - A report of the American College of Cardiology Task Force on Clinical Expert Consensus - Documents developed in collaboration with the European Society of Cardiology endorsed by the Society of Cardiac Angiography and Interventions [J].

Mintz, GS ;

Nissen, SE ;

Anderson, WD ;

Bailey, SR ;

Erbel, R ;

Fitzgerald, PJ ;

Pinto, FJ ;

Rosenfield, K ;

Siegel, RJ ;

Tuzcu, EM ;

Yock, PG .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 37 (05) :1478-1492

[6] A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. [J].

Morice, M ;

Serruys, PW ;

Sousa, JE ;

Fajadet, J ;

Hayashi, EB ;

Perin, M ;

Colombo, A ;

Schuler, G ;

Barragan, P ;

Guagliumi, G ;

Molnar, F ;

Falotico, R .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (23) :1773-1780

[7] Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery [J].

Moses, JW ;

Leon, MB ;

Popma, JJ ;

Fitzgerald, PJ ;

Holmes, DR ;

O'Shaughnessy, C ;

Caputo, RP ;

Kereiakes, DJ ;

Williams, DO ;

Teirstein, PS ;

Jaeger, JL ;

Kuntz, RE .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (14) :1315-1323

[8] A paclitaxel-eluting stent for the prevention of coronary restenosis [J].

Park, SJ ;

Shim, WH ;

Ho, DS ;

Raizner, AE ;

Park, SW ;

Hong, MK ;

Lee, CW ;

Choi, DH ;

Jang, YS ;

Lam, R ;

Weissman, NJ ;

Mintz, GS .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (16) :1537-1545

[9] Vascular responses at proximal and distal edges of paclitaxel-eluting stents - Serial intravascular ultrasound analysis from the TAXUS II trial [J].

Serruys, PW ;

Degertekin, M ;

Tanabe, K ;

Russell, ME ;

Guagliumi, G ;

Webb, J ;

Hamburger, J ;

Rutsch, W ;

Kaiser, C ;

Whitbourn, R ;

Camenzind, E ;

Meredith, I ;

Reeves, F ;

Nienaber, C ;

Benit, E ;

Disco, C ;

Koglin, J ;

Colombo, A .

CIRCULATION, 2004, 109 (05) :627-633

[10] Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) Trial [J].

Serruys, PW ;

Degertekin, M ;

Tanabe, K ;

Abizaid, A ;

Sousa, JE ;

Colombo, A ;

Guagliumi, G ;

Wijns, W ;

Lindeboom, WK ;

Ligthart, J ;

de Feyter, PJ ;

Morice, MC .

CIRCULATION, 2002, 106 (07) :798-803

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