Preparation of Alginate-Based Biomaterials and Their Applications in Biomedicine

被引:245
作者
Zhang, Hengtong [1 ]
Cheng, Junqiu [1 ]
Ao, Qiang [1 ,2 ]
机构
[1] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China
[2] Sichuan Univ, NMPA Key Lab Qual Res & Control Tissue Regenerat, Inst Regulatory Sci Med Devices, NMPA Res Base Regulatory Sci Med Devices, Chengdu 610064, Peoples R China
基金
国家重点研发计划;
关键词
alginate; hydrogel; wound dressing; drug delivery; tissue engineering; MESENCHYMAL STEM-CELLS; CROSS-LINKING; REGENERATIVE MEDICINE; ARTICULAR-CARTILAGE; HYDROGEL MEMBRANES; DRUG-DELIVERY; ORAL DELIVERY; MICROSPHERES; ANTIBACTERIAL; NANOPARTICLES;
D O I
10.3390/md19050264
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Alginates are naturally occurring polysaccharides extracted from brown marine algae and bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be processed into various forms, such as hydrogels, microspheres, fibers and sponges, and have been widely applied in biomedical field. The present review provides an overview of the properties and processing methods of alginates, as well as their applications in wound healing, tissue repair and drug delivery in recent years.
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页数:24
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