RETRACTED: Characterization of enhanced antibacterial effects of novel silver nanoparticles (Retracted Article)

被引:1173
作者
Shrivastava, Siddhartha
Bera, Tanmay
Roy, Arnab
Singh, Gajendra
Ramachandrarao, P.
Dash, Debabrata [1 ]
机构
[1] Banaras Hindu Univ, Inst Med Sci, Dept Biochem, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Inst Technol, Dept Met, Varanasi 221005, Uttar Pradesh, India
[3] Banaras Hindu Univ, Inst Med Sci, Dept Anat, Varanasi 221005, Uttar Pradesh, India
[4] Def Inst Adv Technol, Pune 411025, Maharashtra, India
关键词
D O I
10.1088/0957-4484/18/22/225103
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
In the present study, we report the preparation of silver nanoparticles in the range of 10 - 15 nm with increased stability and enhanced anti-bacterial potency. The morphology of the nanoparticles was characterized by transmission electron microscopy. The antibacterial effect of silver nanoparticles used in this study was found to be far more potent than that described in the earlier reports. This effect was dose dependent and was more pronounced against gram-negative bacteria than gram-positive organisms. Although bacterial cell lysis could be one of the reasons for the observed antibacterial property, nanoparticles also modulated the phosphotyrosine profile of putative bacterial peptides, which could thus affect bacterial signal transduction and inhibit the growth of the organisms.
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页数:9
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