Use of TLC and RPTLC for separation of nicotinic acid derivatives

被引：8
作者：
Pyka, A
Niestroj, A
Szarkowicz, A
Sliwiok, J
机构：
[1] L Warynski Silesian Med Acad, Fac Pharm, PL-41200 Sosnowiec, Poland
[2] Silesian Univ, Inst Chem, PL-40006 Katowice, Poland
来源：
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC | 2002年 / 15卷 / 06期
关键词：
nicotinic acid; nicotinamide; nicotinic acid derivatives; TLC; RPTLC; pharmaceutical analysis; retention-mobile phase composition relationships;
D O I：
10.1556/JPC.15.2002.6.3
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Separations of nicotinic acid and its derivatives on different stationary phases (silica gel, a mixture of silica gel and kieseiguhr, polyamide 11, and RP-18) have been compared. Relationships between R-M values and mobile-phase composition were determined for ten nicotinic acid derivatives. The results can be used to predict conditions suitable for extraction of the derivatives of nicotinic acid investigated.
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收藏
页码：410 / 413
页数：4
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