Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in ovariectomized rats

被引：25
作者：
Liang, Yong-Qiang [1 ,2 ]
Qi, Meng-Chun [2 ]
Xu, Jiang [3 ]
Xu, Juan [1 ]
Liu, Hua-Wei [1 ]
Dong, Wei [2 ]
Li, Jin-Yuan [2 ]
Hu, Min [1 ]
机构：
[1] Chinese Peoples Liberat Army Gen Hosp, Dept Stomatol, Beijing 100853, Peoples R China
[2] Hebei United Univ, Coll Stomatol, Tangshan 063000, Hebei, Peoples R China
[3] Tongchuan City Peoples Hosp, Dept Stomatol, Tongchuan 727100, Shaanxi, Peoples R China
来源：
MOLECULAR MEDICINE REPORTS | 2014年 / 10卷 / 06期
基金：
中国国家自然科学基金;
关键词：
low-magnitude high-frequency loading; whole-body vibration; osteoporosis; dental implants; osseointegration; rat; TITANIUM IMPLANTS; ZOLEDRONIC ACID; MECHANICAL SIGNALS; OSTEOPOROTIC RATS; DENTAL IMPLANTS; BONE-FORMATION; OSTEONECROSIS; FIXATION; FAILURES; OUTCOMES;
D O I：
10.3892/mmr.2014.2597
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Osteoporosis deteriorates jaw bone quality and may compromise early implant osseointegration and early implant loading. The influence of low-magnitude, high-frequency (LMHF) vibration on pen-implant bone healing and implant integration in osteoporotic bones remains poorly understood. LMHF loading via whole-body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone-to-implant contact, pen-implant bone fraction and implant mechanical properties in osteoporotic rats. In the present study, LMHF loading by WBV was performed in osteoporotic rats-, with a loading duration of 4 weeks during the early stages of bone healing. The results indicated that 4-week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early pen-implant osseointegration in ovariectomized rats.
引用
收藏
页码：2835 / 2842
页数：8
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