Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging

被引:494
作者
Rao, Lang [1 ]
Bu, Lin-Lin [2 ]
Cai, Bo [1 ]
Xu, Jun-Hua [1 ]
Li, Andrew [3 ]
Zhang, Wen-Feng [2 ]
Sun, Zhi-Jun [2 ]
Guo, Shi-Shang [1 ]
Liu, Wei [1 ,4 ]
Wang, Tza-Huei [3 ,4 ]
Zhao, Xing-Zhong [1 ]
机构
[1] Wuhan Univ, Sch Phys & Technol, Minist Educ, Key Lab Artificial Micro & Nanostruct, Wuhan 430072, Hubei, Peoples R China
[2] Wuhan Univ, Sch & Hosp Stomatol, Dept Oral Maxillofacial Head Neck Oncol, Wuhan 430079, Hubei, Peoples R China
[3] Johns Hopkins Sch Med, Dept Biomed Engn, Baltimore, MD 21205 USA
[4] Johns Hopkins Univ, Dept Mech Engn, Baltimore, MD 21218 USA
基金
中国国家自然科学基金;
关键词
THOMSEN-FRIEDENREICH ANTIGEN; DRUG-DELIVERY; HUMAN BREAST; IN-VITRO; NANOPARTICLES; FLUORESCENCE; ADHESION; NANOCRYSTALS; CIRCULATION; STRATEGIES;
D O I
10.1002/adma.201506086
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cancer cell membrane-coated upconversion nanoprobes (CC-UCNPs) with immune escape and homologous targeting capabilities are used for highly specific tumor imaging. The combination of UCNPs with biomimetic cancer cell membranes embodies a novel materials design strategy and presents a compelling class of advanced materials.
引用
收藏
页码:3460 / +
页数:8
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