Hand eczema is common and multifactorial

被引:51
作者
Coenraads, Pieter-Jan [1 ]
机构
[1] Univ Groningen, Med Ctr, Dept Dermatol, NL-9700 RB Groningen, Netherlands
关键词
D O I
10.1038/sj.jid.5700781
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Clinicians agree that hand eczema is multifactorial, although there are many uncertainties regarding causative factors. Atopic dermatitis is assumed to be a major risk factor, whereas the role of allergies is overestimated. Twin studies may shed light on the contribution of other endogenous, possibly genetic factors versus the role of exposure to environmental agents, with the latter being amenable to prevention and intervention.
引用
收藏
页码:1568 / 1570
页数:3
相关论文
共 10 条
[1]   Genetic factors in nickel allergy evaluated in a population-based female twin sample [J].
Bryld, LE ;
Hindsberger, C ;
Kyvik, KO ;
Agner, T ;
Menné, T .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 123 (06) :1025-1029
[2]   The gene for a rare autosomal dominant form of pompholyx maps to chromosome 18q22.1-18q22.3 [J].
Chen, Jian-Jun ;
Liang, Yan-Hua ;
Zhou, Fu-Sheng ;
Yang, Sen ;
Wang, Jian ;
Wang, Pei-Guang ;
Du, Wen-Hui ;
Xu, Shi-Jie ;
Huang, Wei ;
Zhang, Xue-Jun .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 (02) :300-304
[3]   Occupational skin-disease data in Europe [J].
Diepgen, TL .
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2003, 76 (05) :331-338
[4]   How atopic is atopic dermatitis? [J].
Flohr, C ;
Johansson, SGO ;
Wahlgren, CF ;
Williams, H .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 114 (01) :150-158
[5]   Breaking the (Un)sound barrier: Filaggrin is a major gene for atopic dermatitis [J].
Irvine, Alan D. ;
Irwin McLean, W. H. .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 (06) :1200-1202
[6]   Heritability of hand eczema is not explained by comorbidity with atopic dermatitis [J].
Lerbaek, Anne ;
Kyvik, Kirsten O. ;
Mortensen, Jakob ;
Bryld, Lars E. ;
Menne, Torkil ;
Agner, Tove .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 (07) :1632-1640
[7]   Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis [J].
McLean, W. H. Irwin ;
Hull, Peter R. .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 (01) :8-10
[8]   Incidence of hand eczema -: A population-based retrospective study [J].
Meding, B ;
Järvholm, B .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 122 (04) :873-877
[9]   SUSCEPTIBILITY TO AND INCIDENCE OF HAND DERMATITIS IN A COHORT OF APPRENTICE HAIRDRESSERS AND NURSES [J].
SMIT, HA ;
VANRIJSSEN, A ;
VANDENBROUCKE, JP ;
COENRAADS, PJ .
SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH, 1994, 20 (02) :113-121
[10]  
SVENSSON A, 1988, ACTA DERM-VENEREOL, V68, P509