Influence of matrigel on the shape and dynamics of cancer cells

被引：1

作者：

Ye, Teng ^{[1
]}

Qiu, Feng ^{[1
,2
]}

机构：

[1] Nanchang Univ, Clin Med Coll 1, Nanchang 330006, Jiangxi, Peoples R China

[2] Nanchang Univ, Affiliated Hosp 1, Dept Oncol, Nanchang 330006, Jiangxi, Peoples R China

来源：

CHINESE PHYSICS B | 2019年 / 28卷 / 10期

关键词：

cancer cell; matrigel; migration; shape deformation; BASEMENT-MEMBRANE MATRIX; BREAST;

D O I：

10.1088/1674-1056/ab4275

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The interaction between extracellular matrices and cancer cells plays an important role in regulating cancer cell behaviors. In this article, we use matrigel to mimic extracellular matrices and investigate experimentally how matrigel influences the shape and dynamics of breast cancer cells (MDA-MB-231-GFP cells). We find that matrigel facilitates cancer cells' migration and shape deformation. The influences of the matrigel concentration are also reported.

引用

页数：4

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