Dual functions of Streptococcus salivarius urease

被引：67

作者：

Chen, YYM

Weaver, CA

Burne, RA

机构：

[1] Univ Rochester, Med Ctr, Sch Med & Dent, Ctr Oral Biol, Rochester, NY 14642 USA

[2] Univ Rochester, Sch Med & Dent, Dept Microbiol & Immunol, Rochester, NY 14642 USA

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 16期

关键词：

D O I：

10.1128/JB.182.16.4667-4669.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A urease-deficient derivative of Streptococcus salivarius 57.I was constructed by allelic exchange at the ureC locus. The wild-type strain was protected against acid killing through hydrolysis of physiologically relevant concentrations of urea, whereas the mutant was not. Also, S. salivarius could use urea as a source of nitrogen for growth exclusively through a urease-dependent pathway.

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页码：4667 / 4669

页数：3

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