Catalytic C-C bond forming transformations via direct β-C-H functionalization of carbonyl compounds

被引：88

作者：

Huang, Zhongxing ^{[1
]}

Dong, Guangbin ^{[1
]}

机构：

[1] Univ Texas Austin, Dept Chem, Austin, TX 78712 USA

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 43期

关键词：

C-H functionalization; Carbonyl compounds; beta-C-H bonds; C-C bond formation; UNACTIVATED C(SP(3))-H BONDS; KETO-ESTERS; STEREOSELECTIVE-SYNTHESIS; INTERMOLECULAR ARYLATION; ACTIVATION; AMINO; ALDEHYDES; ALKYLATION; SP(2); OLEFINATION;

D O I：

10.1016/j.tetlet.2014.09.005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Strategies have emerged over the past decade to enable the direct functionalization of the remote and inert beta-C-H bonds of carbonyl compounds. Based on these strategies, a wide collection of novel beta-C-C bond formation transformations have been developed, including arylation, alkylation, alkenylation, alkynylation, and carbonylation. This review summarizes these recent methods for C-C bond formations via direct beta-C-H functionalization of carbonyl compounds. The scope and limitation of each strategy are also discussed. (C) 2014 Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.

引用

收藏

页码：5869 / 5889

页数：21

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