Catalytic C-C bond forming transformations via direct β-C-H functionalization of carbonyl compounds

被引：88
作者：
Huang, Zhongxing [1 ]
Dong, Guangbin [1 ]
机构：
[1] Univ Texas Austin, Dept Chem, Austin, TX 78712 USA
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 43期
关键词：
C-H functionalization; Carbonyl compounds; beta-C-H bonds; C-C bond formation; UNACTIVATED C(SP(3))-H BONDS; KETO-ESTERS; STEREOSELECTIVE-SYNTHESIS; INTERMOLECULAR ARYLATION; ACTIVATION; AMINO; ALDEHYDES; ALKYLATION; SP(2); OLEFINATION;
D O I：
10.1016/j.tetlet.2014.09.005
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Strategies have emerged over the past decade to enable the direct functionalization of the remote and inert beta-C-H bonds of carbonyl compounds. Based on these strategies, a wide collection of novel beta-C-C bond formation transformations have been developed, including arylation, alkylation, alkenylation, alkynylation, and carbonylation. This review summarizes these recent methods for C-C bond formations via direct beta-C-H functionalization of carbonyl compounds. The scope and limitation of each strategy are also discussed. (C) 2014 Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
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收藏
页码：5869 / 5889
页数：21
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