Larvicidal activity of oil-resin fractions from the Brazilian medicinal plant Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) against Aedes aegypti (Diptera, Culicidae)

被引：23
|
作者：
da Silva, Heloisa Helena Garcia
Geris, Regina
Rodrigues Filho, Edson
Rocha, Cleonice
da Silva, Ionizete Garcia
机构：
[1] Univ Fed Goias, Dept Microbiol Imunol Parasitol & Patol, IPTSP, BR-74001970 Goiania, Go, Brazil
[2] Univ Fed Bahia, Inst Quim, Salvador, BA, Brazil
[3] Univ Fed Sao Carlos, Dept Quim, BR-13560 Sao Carlos, SP, Brazil
[4] Univ Catolica Goias, Goiania, Go, Brazil
来源：
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2007年 / 40卷 / 03期
关键词：
Copaifera reticulata; Aedes aegypti; terpenoids; larvicidal activity;
D O I：
10.1590/S0037-86822007000300002
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Oil-resin fractions from Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) were evaluated for larvicidal activity on third larval instars of Aedes aegypti, in searching for alternative control methods for this mosquito. The bioactive fractions were chemically monitored by thin layer chromatography, H-1 and C-13 nuclear magnetic resonance and mass spectrometry. Bioassays were performed using five repetitions, at a temperature of 28 +/- 1 degrees C, relative humidity of 80 +/- 5% and light and dark cycles of 12h. Mortality was indicated by darkening of the cephalic capsule after 24h of exposure of the larvae to the solutions. The most active fractions were CRM1-4 (sesquiterpenes) and CRM5-7 (labdane diterpenes), which showed LC50 values of 0.2 and 0.8ppm, respectively
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页码：264 / 267
页数：4
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