Quinoline and 2-nitroimino-1, 3-diazacycloalkane hybrids: Design, synthesis and insecticidal activity

被引：3

作者：

Sowmya, Jonnalagadda ^{[1
]}

Padma, Banda ^{[1
]}

Leelavathi, Panaganti ^{[1
]}

机构：

[1] Osmania Univ Hyderabad, Univ Coll Sci, Dept Chem, Hyderabad 500007, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2022年 / 99卷 / 01期

关键词：

Neonicotinoid analogues; Imidacloprid; Quinoline; Safflower aphids; PTC; Insecticidal activity; DERIVATIVES; NEONICOTINOIDS; ANTICANCER; RESISTANCE; SAFFLOWER; ANALOGS;

D O I：

10.1016/j.jics.2021.100279

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A library of new hybrid molecules comprising quinoline, 2-nitroimino-1, 3-diazacycloalkane motifs were designed and synthesized as plausible neonicotinoid analogues. These compounds were synthesized from 2-chloro/aryloxy3-formyl quinolines and guanidine nitrate with the coupling of 2-chloro/aryloxy-3-(chloromethyl)quinolines, 2nitroimino-1, 3-diazacycloalkanes under phase transfer catalysis (PTC) as crucial step. All the compounds were obtained in excellent yields (80-90%) and were characterized by 1H, 13C NMR and mass spectrometry. The newly generated compounds were screened for insecticidal activity against aphids in safflower field and some of them displayed moderate activity.

引用

页数：6

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