Macroporous hydrogels based on 2-hydroxyethyl methacrylate.: Part 1.: Copolymers of 2-hydroxyethyl methacrylate with methacrylic acid

被引:35
作者
Prádny, M
Lesny, P
Fiala, J
Vacík, J
Slouf, M
Michálek, J
Syková, E
机构
[1] Acad Sci Czech Republ, Inst Macromol Chem, CR-16206 Prague 6, Czech Republic
[2] Charles Univ, Ctr Cell Therapy & Tissue Repair, Prague 15006 5, Czech Republic
[3] Acad Sci Czech Republ, Inst Expt Med, Prague 14220 4, Czech Republic
关键词
diffusion; hydrogels; 2-hydroxyethyl methacrylate; macroporous polymers; morphology; polyanions; gels;
D O I
10.1135/cccc20030812
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of macroporous crosslinked copolymers of 2-hydroxyethyl methacrylate (HEMA) with methacrylic acid (MA) was prepared in the presence of fractionated particles of sodium chloride. The hydrogels were characterized by the number of pores in unit volume, the pore size, the water content in pores and diffusion parameters. The structure of the hydrogels was followed by confocal and scanning electron microscopy.
引用
收藏
页码:812 / 822
页数:11
相关论文
共 13 条
[1]  
[Anonymous], [No title captured]
[2]  
ANTONSEN KP, 1993, BIOMAT ARTIF CELL IM, V21, P1
[3]   ENTRAPMENT OF BIOMOLECULES INTO HYDROGELS OBTAINED BY RADIATION-INDUCED POLYMERIZATION [J].
CARENZA, M ;
VERONESE, FM .
JOURNAL OF CONTROLLED RELEASE, 1994, 29 (1-2) :187-193
[4]  
HALD0N R.A., 1972, BRIT POLYM J, V4, P491
[5]   Acceleration of deswelling of poly(N-isopropylacrylamnide) hydrogel by the treatment of a freeze-dry and hydration process [J].
Kato, N ;
Takahashi, F .
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1997, 70 (06) :1289-1295
[6]   Preparation of macroporous poly(2-hydroxyethyl methacrylate) hydrogels by enhanced phase separation [J].
Liu, Q ;
Hedberg, EL ;
Liu, ZW ;
Bahulekar, R ;
Meszlenyi, RK ;
Mikos, AG .
BIOMATERIALS, 2000, 21 (21) :2163-2169
[7]   Extracellular space structure revealed by diffusion analysis [J].
Nicholson, C ;
Syková, E .
TRENDS IN NEUROSCIENCES, 1998, 21 (05) :207-215
[8]   MACROPOROUS HYDROGELS FOR BIOMEDICAL APPLICATIONS - METHODOLOGY AND MORPHOLOGY [J].
OXLEY, HR ;
CORKHILL, PH ;
FITTON, JH ;
TIGHE, BJ .
BIOMATERIALS, 1993, 14 (14) :1064-1072
[9]   Novel alginate sponges for cell culture and transplantation [J].
Shapiro, L ;
Cohen, S .
BIOMATERIALS, 1997, 18 (08) :583-590
[10]   NOVEL MACROPOROUS HYDROGEL ADSORBENTS FOR ARTIFICIAL LIVER SUPPORT HEMOPERFUSION SYSTEMS [J].
SKELLY, PJ ;
TIGHE, BJ .
POLYMER, 1979, 20 (09) :1051-1052