Enantioselective construction of allylic phosphine oxides through substitution of Morita-Baylis-Hillman carbonates with phosphine oxides

被引：85
|
作者：
Hong, Liang [1 ,2 ]
Sun, Wangsheng [1 ,2 ]
Liu, Chunxia [1 ,2 ]
Zhao, Depeng [1 ,2 ]
Wang, Rui [1 ,2 ,3 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Inst Biochem & Mol Biol, Lanzhou 730000, Peoples R China
[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 16期
关键词：
ORGANOCATALYTIC ASYMMETRIC HYDROPHOSPHINATION; FRIEDEL-CRAFTS ALKYLATION; ALPHA; BETA-UNSATURATED ALDEHYDES; DIPHENYL PHOSPHITE; CONJUGATE ADDITION; GAMMA-BUTENOLIDES; MICHAEL ADDITION; ALPHA-AMINO; LIGANDS; HYDROPHOSPHONYLATION;
D O I：
10.1039/b926037d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The asymmetric organocatalytic allylic substitution reaction of MBH carbonates with phosphine oxides has been developed. This organocatalytic approach constitutes an easy and efficient method for the direct preparation of allylic phosphine oxides in high enantioselectivities.
引用
收藏
页码：2856 / 2858
页数：3
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