In the L-His + H2SO4 + H2O system, in addition to known 2L-His center dot 2H(2)SO(4)center dot 3H(2)O and L-His-H2SO4 crystals, new crystalline compounds 2L-His center dot H2SO4 center dot H2O and 2L-His-H2SO4 have been obtained. The better quality of 2L-His center dot H2SO4 center dot H2O allowed determining its crystal structure. IR and Raman spectra of the crystals are shown and discussed. The crystals Of L-histidine sulfates are not noticeable by their nonlinear optical properties. (c) 2009 Elsevier B.V. All rights reserved.