Oxidative decarboxylation of α-hydroxy acids by a functional model of the nonheme iron oxygenase, CloR

被引：25

作者：

Paine, Tapan Kanti ^{[1
]}

Paria, Sayantan ^{[1
]}

Que, Lawrence, Jr. ^{[2
,3
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Inorgan Chem, Kolkata 700032, India

[2] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

[3] Univ Minnesota, Ctr Met Biocatalysis, Minneapolis, MN 55455 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 11期

基金：

美国国家卫生研究院;

关键词：

2-HIS-1-CARBOXYLATE FACIAL TRIAD; COMPLEXES; ENZYMES; BIOSYNTHESIS; CHEMISTRY; CLEAVAGE; BINDING; BOND;

D O I：

10.1039/b925389k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iron(II)-alpha-hydroxy acid complexes of a tripodal N4 ligand undergo oxidative decarboxylation upon exposure to O-2 and mimic the aliphatic C1-C2 cleavage step catalyzed by CloR.

引用

页码：1830 / 1832

页数：3

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