Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan-Pt-Fe3O4 Hybrid Nanoparticles

被引:6
作者
Kumari, Sangeeta [1 ]
Singh, Raj Pal [2 ]
Chavan, Nayaku N. [3 ]
Sahi, Shivendra V. [1 ]
Sharma, Nilesh [4 ]
机构
[1] Univ Sci, Dept Biol Sci, Philadelphia, PA 19104 USA
[2] Bharati Vidyapeeth Univ, Adv Res Ctr Pharmaceut Sci & Appl Chem, Pune 411038, Maharashtra, India
[3] CSIR Natl Chem Lab, Div Polymer Sci & Engn, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India
[4] Western Kentucky Univ, Dept Biol, 1906 Coll Hts Blvd, Bowling Green, KY 42101 USA
基金
美国国家科学基金会;
关键词
chitosan; Pt-Fe3O4 hybrid nanoparticles; thermogravimetric analysis; nanocomposite films; tensile strength testing; MAGNETIC NANOPARTICLES; NANOHYBRID SCAFFOLD; CHITOSAN; HETERODIMERS; PROPERTY; GROWTH; ACID;
D O I
10.3390/nano11051275
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The development of organic-inorganic hybrids or nanocomposite films is increasingly becoming attractive in light of their emerging applications. This research focuses on the formation of a unique nanocomposite film with enhanced elasticity suitable for many biomedical applications. The physical property measurement system and transmission electron microscopy were used to analyze Pt-Fe3O4 hybrid nanoparticles. These nanohybrids exhibited magnetic effects. They were further exploited to prepare the nanocomposite films in conjunction with a chitosan-g-glycolic acid organic fraction. The nanocomposite films were then examined using standard techniques: thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and atomic force microscopy. Tensile strength testing demonstrated a significantly greater elastic strength of these nanocomposite films than pure chitosan films. The water absorption behavior of the nanocomposites was evaluated by measuring swelling degree. These nanocomposites were observed to have substantially improved physical properties. Such novel nanocomposites can be extended to various biomedical applications, which include drug delivery and tissue engineering.
引用
收藏
页数:12
相关论文
共 42 条
[1]   Polymer Blending as a Novel Approach for Tuning the SPR Peaks of Silver Nanoparticles [J].
Aziz, Shujahadeen B. ;
Abdulwahid, Rebar T. ;
Rasheed, Mariwan A. ;
Abdullah, Omed Gh ;
Ahmed, Hameed M. .
POLYMERS, 2017, 9 (10) :486
[2]   Electro-optical shifts in silver nanoparticle films [J].
Chapman, R ;
Mulvaney, P .
CHEMICAL PHYSICS LETTERS, 2001, 349 (5-6) :358-362
[3]  
Chen RH, 1996, CARBOHYD POLYM, V29, P353
[4]   Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions [J].
Cheng, MY ;
Deng, JU ;
Yang, F ;
Gong, YD ;
Zhao, NM ;
Zhang, XF .
BIOMATERIALS, 2003, 24 (17) :2871-2880
[5]   Chitosan films for regenerative medicine: fabrication methods and mechanical characterization of nanostructured chitosan films [J].
De Masi A. ;
Tonazzini I. ;
Masciullo C. ;
Mezzena R. ;
Chiellini F. ;
Puppi D. ;
Cecchini M. .
Biophysical Reviews, 2019, 11 (5) :807-815
[6]   Preparation and characterization of novel hybrid of chitosan-g-lactic acid and montmorillonite [J].
Depart, Dilip ;
Kumar, Annamalai Pratheep ;
Singh, Raj Pal .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2006, 78A (02) :372-382
[7]   Magnetic nanoparticles for drug delivery [J].
Dobson, J .
DRUG DEVELOPMENT RESEARCH, 2006, 67 (01) :55-60
[8]   A layer-by-layer film of chitosan in a taste sensor application [J].
dos Santos, DS ;
Riul, A ;
Malmegrim, RR ;
Fonseca, FJ ;
Oliveira, ON ;
Mattoso, LHC .
MACROMOLECULAR BIOSCIENCE, 2003, 3 (10) :591-595
[9]   Composites of polymeric gels and magnetic nanoparticles: Preparation and drug release behavior [J].
Francois, Nora J. ;
Allo, Sabina ;
Jacobo, Silvia E. ;
Daraio, Marta E. .
JOURNAL OF APPLIED POLYMER SCIENCE, 2007, 105 (02) :647-655
[10]  
Gomez-Romero P., 2004, FUNCTIONAL HYBRID MA, P50