Synthesis, antimicrobial and QSAR studies of novel benzenesulfonamide derivatives

被引：0
作者：
Zengin, Gulay [1 ]
Zengin, Huseyin [1 ]
Turkmen, Hasan [2 ]
Digrak, Metin [3 ]
机构：
[1] Gaziantep Univ, Fac Sci & Literature, Dept Chem, TR-27310 Gaziantep, Turkey
[2] Harran Univ, Dept Med Pharmacol, Fac Med, TR-63190 Sanliurfa, Turkey
[3] Kahramanmaras Sutcu Imam Univ, Fac Sci & Literature, Dept Biol, TR-46100 Kahramanmaras, Turkey
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2018年 / 57卷 / 06期
关键词：
Benzenesulfonamide; antimicrobial activity; QSAR studies; fluorescence; SULFONAMIDES; INHIBITORS; XII;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel benzenesulfonamide derivatives have been synthesized and characterized by various spectroscopical and analytical techniques, such as, FT-IR, UV-Vis, and NMR, and elemental analysis. The derivatives synthesized have been tested for in vitro antimicrobial activities against several microorganisms using the disc diffusion method, wherein a broad spectrum of activity has been observed with inhibition zones in the range 10-32 mm. Photoluminescence properties have been evaluated and a QSAR investigation on the compounds synthesized has been carried out to reveal correlations between various physicochemical parameters and antimicrobial activity.
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收藏
页码：852 / 857
页数：6
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