Palladium-catalyzed oxidation of primary and secondary allylic and benzylic alcohols

被引：359
作者：
Peterson, KP [1 ]
Larock, RC [1 ]
机构：
[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 10期
关键词：
D O I：
10.1021/jo971268k
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient procedure for the oxidation of primary and secondary allylic and benzylic alcohols to aldehydes and ketones, respectively, has been achieved using catalytic Pd(OAc)(2) in dimethyl sulfoxide (DMSO) with oxygen gas as the sole reoxidant of the palladium. Secondary substrates show increased reaction rates and improved yields with the addition of 2 equiv of NaHCO3. The reactions are free of acetal/ketal and ester byproducts.
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页码：3185 / 3189
页数：5
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