β-catenin:: A pivot between cell adhesion and Wnt signalling

被引：247

作者：

Bienz, M ^{[1
]}

机构：

[1] MRC Lab Mol Biol, Cambridge CB2 2QH, England

来源：

CURRENT BIOLOGY | 2005年 / 15卷 / 02期

关键词：

D O I：

10.1016/j.cub.2004.12.058

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mutual adhesion of animal cells is intimately linked to Wnt signaling through a shared component: β-catenin, or Armadillo in Drosophila. Recent work indicates how β-catenin shifts from cell adhesion to Wnt signaling, a switch associated with epithelial-mesenchymal transitions and cancer.

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页码：R64 / R67

页数：4

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