Synthesis of polycyclic 3,3 ' -spirooxindoles and some new 2-arylquinoxalines from ( E/Z )-1-(2-oxo-2-arylethylidene)-5,6-dihydro-4 H -pyrrolo[3,2,1-ij ]quinolin-2(1 H )-ones

被引：2

作者：

Saatluo, Bahman Ebrahimi ^{[1
,2
]}

Amanollahi, Ruhollah ^{[1
]}

Fazlelahi, Hadi Zare ^{[1
]}

Baradarani, Mehdi M. ^{[1
]}

Joule, John A. ^{[3
]}

机构：

[1] Urmia Univ, Fac Chem, Dept Organ Chem, Orumiyeh 57153, Iran

[2] Iranian Acad Ctr Educ Culture & Res ACECR, Orumiyeh 57155397, Iran

[3] Univ Manchester, Chem Dept, Manchester M13 9PL, Lancs, England

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2022年 / 1255卷

关键词：

Arylquinoxaline; Spirooxindole; Pyrroloquinoline; Diazepine; Spirocyclodiazepine; INDOLE; BENZODIAZEPINE; DERIVATIVES; INHIBITORS;

D O I：

10.1016/j.molstruc.2022.132445

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A facile protocol to access a novel series of spirocyclodiazepines from cyclocondensation of 1-(2oxo-2-arylethylidene)-5,6-dihydro-4 H -pyrrolo[3,2,1- ij ]quinolin-2(1 H )-ones (derived from 5,6-dihydro-1 H pyrrolo[3,2,1- ij ]quinolone-1,2(4 H )-dione) with ethane-1,2-diamines and benzene-1,2-diamines, generates polycyclic spirooxindoles and unexpectedly produces 2-arylquinoxalines instead of spiro[ indole -1,5benzodiazepines ], respectively, in the presence of p -TSA as an efficient catalyst in a green solvent.(c) 2022 Elsevier B.V. All rights reserved.

引用

页数：7

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