KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia

被引：30

作者：

Medves, S. ^{[1
]}

Duhoux, F. P. ^{[2
]}

Ferrant, A. ^{[3
]}

Toffalini, F. ^{[1
]}

Ameye, G. ^{[2
]}

Libouton, J-M ^{[2
]}

Poirel, H. A. ^{[2
]}

Demoulin, J-B ^{[1
]}

机构：

[1] Catholic Univ Louvain, Duve Inst, B-1200 Brussels, Belgium

[2] Catholic Univ Louvain, Clin Univ St Luc, Ctr Human Genet, B-1200 Brussels, Belgium

[3] Catholic Univ Louvain, Clin Univ St Luc, Hematol Unit, B-1200 Brussels, Belgium

来源：

LEUKEMIA | 2010年 / 24卷 / 05期

关键词：

MYELOPROLIFERATIVE DISORDERS; ACTIVATION;

D O I：

10.1038/leu.2010.13

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1052 / 1055

页数：5

共 8 条

[1] A novel ETV6-PDGFRB fusion transcript missed by standard screening in a patient with an imatinib responsive chronic myeloproliferative disease [J].

Curtis, C. E. ;

Grand, F. H. ;

Waghorn, K. ;

Sahoo, T. P. ;

George, J. ;

Cross, N. C. P. .

LEUKEMIA, 2007, 21 (08) :1839-1841

[2] Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders [J].

David, Marianna ;

Cross, Nicholas C. P. ;

Burgstaller, Sonja ;

Chase, Andrew ;

Curtis, Claire ;

Dang, Raymond ;

Gardembas, Martine ;

Goldman, John M. ;

Grand, Francis ;

Hughes, George ;

Huguet, Francoise ;

Lavender, Louise ;

McArthur, Grant A. ;

Mahon, Francois X. ;

Massimini, Giorgio ;

Melo, Junia ;

Rousselot, Philippe ;

Russell-Jones, Robin J. ;

Seymour, John F. ;

Smith, Graeme ;

Stark, Alastair ;

Waghorn, Katherine ;

Nikolova, Zariana ;

Apperley, Jane F. .

BLOOD, 2007, 109 (01) :61-64

[3] Oncogenic derivatives of platelet-derived growth factor receptors [J].

Jones, AV ;

Cross, NCP .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2004, 61 (23) :2912-2923

[4] Kank proteins: structure, functions and diseases [J].

Kakinuma, N. ;

Zhu, Y. ;

Wang, Y. ;

Roy, B. C. ;

Kiyama, R. .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2009, 66 (16) :2651-2659

[5] Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2 [J].

Kralovics, R ;

Teo, SS ;

Buser, AS ;

Brutsche, M ;

Tiedt, R ;

Tichelli, A ;

Passamonti, F ;

Pietra, D ;

Cazzola, M ;

Skoda, RC .

BLOOD, 2005, 106 (10) :3374-3376

[6] Deletion of the ANKRD15 gene at 9p24.3 causes parent-of-origin-dependent inheritance of familial cerebral palsy [J].

Lerer, I ;

Sagi, M ;

Meiner, V ;

Cohen, T ;

Zlotogora, J ;

Abeliovich, D .

HUMAN MOLECULAR GENETICS, 2005, 14 (24) :3911-3920

[7] Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms [J].

Tefferi, A. ;

Vardiman, J. W. .

LEUKEMIA, 2008, 22 (01) :14-22

[8] Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization [J].

Yang, Yan ;

Yuzawa, Satoru ;

Schlessinger, Joseph .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (22) :7681-7686

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