What happens after early intervention in first-episode psychosis? Limitations of existing service models and an agenda for the future

被引:6
作者
Hyatt, Andrew S. [1 ,2 ]
Hasler, Victoria [1 ,2 ]
Wilner, Emily K. [1 ,2 ]
机构
[1] Cambridge Hlth Alliance, Dept Psychiat, 1493 Cambridge St,Macht Bldg Rm 206, Cambridge, MA 02139 USA
[2] Harvard Med Sch, Dept Psychiat, Boston, MA 02115 USA
关键词
coordinated specialty care; early intervention; psychosis; psychosocial interventions; RANDOMIZED CONTROLLED-TRIAL; 1ST EPISODE; PROGRAM; OUTCOMES; SCHIZOPHRENIA; PREDICTORS; RELAPSE; CARE;
D O I
10.1097/YCO.0000000000000785
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Purpose of review Early intervention in first-episode psychosis (FEP) improves symptomatic and functional outcomes while programs last. However, these gains may not be sustained over time and not all individuals benefit equally from such programs. This review examines the efficacy of FEP programs, as well as step-down practices and long-term outcomes to identify ways to extend the gains made in FEP programs. Recent findings FEP programs improve outcomes while services last, but effects diminish over time. Step-down and discharge practices vary widely with little randomized evidence guiding practice. Extending the duration of FEP programs for all does not consistently improve outcomes, but there is some encouraging evidence that targeted psychosocial interventions after program end may extend symptomatic and functional benefits. Members of marginalized groups and individuals with poorer outcomes during the FEP period may benefit from further specialized intervention after FEP. Step down practices from FEP programs should be structured and tailored to individual needs, and benefit from sustained connections to community resources. Psychosocial interventions like social skills training, peer support, and supported education and employment may help extend the benefit of FEP programs after more intensive services end.
引用
收藏
页码:165 / 170
页数:6
相关论文
共 50 条
  • [31] Predictors of functioning in people suffering from first-episode psychosis 1 year into entering early intervention service in Hong Kong
    Chong, Catherine Shiu-yin
    Siu, Man-Wah
    Kwan, Condy Hoi-shuen
    Chang, Wing-Chung
    Lee, Edwin Ho-ming
    Chan, Sherry Kit-wa
    Hui, Christy Lai-ming
    Tam, Fiona Yee-ki
    Chen, Eric Yu-hai
    Lo, William Tak-lam
    EARLY INTERVENTION IN PSYCHIATRY, 2018, 12 (05) : 828 - 838
  • [32] The Early Psychosis Intervention Center (EPICENTER): development and six-month outcomes of an American first-episode psychosis clinical service
    Breitborde, Nicholas J. K.
    Bell, Emily K.
    Dawley, David
    Woolverton, Cindy
    Ceaser, Alan
    Waters, Allison C.
    Dawson, Spencer C.
    Bismark, Andrew W.
    Polsinelli, Angelina J.
    Bartolomeo, Lisa
    Simmons, Jessica
    Bernstein, Beth
    Harrison-Monroe, Patricia
    BMC PSYCHIATRY, 2015, 15
  • [33] Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis
    Chang, Wing Chung
    Kwong, Vivian Wing Yan
    Lau, Emily Sin Kei
    So, Hon Cheong
    Wong, Corine Sau Man
    Chan, Gloria Hoi Kei
    Jim, Olivia Tsz Ting
    Hui, Christy Lai Ming
    Chan, Sherry Kit Wa
    Lee, Edwin Ho Ming
    Chen, Eric Yu Hai
    BRITISH JOURNAL OF PSYCHIATRY, 2017, 211 (01) : 37 - 44
  • [34] Whispering on the Water British Pakistani Families' Experiences of Support From an Early Intervention Service for First-Episode Psychosis
    Penny, Elizabeth
    Newton, Elizabeth
    Larkin, Michael
    JOURNAL OF CROSS-CULTURAL PSYCHOLOGY, 2009, 40 (06) : 969 - 987
  • [35] Cognitive remediation combined with an early intervention service in first episode psychosis
    Christensen, T. Ostergaard
    Vesterager, L.
    Krarup, G.
    Olsen, B. B.
    Melau, M.
    Gluud, C.
    Nordentoft, M.
    ACTA PSYCHIATRICA SCANDINAVICA, 2014, 130 (04) : 300 - 310
  • [36] Trajectories of suicidality during a 2-year early-intervention program for first-episode psychosis: A longitudinal study
    Moro, Laura
    Sicotte, Roxanne
    Joober, Ridha
    Malla, Ashok
    Lepage, Martin
    Orri, Massimiliano
    PSYCHIATRY RESEARCH, 2024, 340
  • [37] Adolescents with first-episode psychosis and clinical high risk in the Province of Ferrara: an audit on the implementation of a specialised early intervention program
    Magnabosco, Vittoria
    Ferrara, Maria
    Domenicano, Ilaria
    Cruciata, Marco
    Sarela, Antonia Ioanna
    Emanuelli, Franca
    Grassi, Luigi
    INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, 2025, : 224 - 234
  • [38] Co-occurring first-episode psychosis and borderline personality pathology in an early intervention for psychosis cohort
    Schandrin, Aurelie
    Francey, Shona
    Nguyen, Lucia
    Whitty, Dean
    McGorry, Patrick
    Chanen, Andrew M.
    O'Donoghue, Brian
    EARLY INTERVENTION IN PSYCHIATRY, 2023, 17 (06) : 588 - 596
  • [39] Negative symptoms in first-episode psychosis: Clinical correlates and 1-year follow-up outcomes in London Early Intervention Services
    Rammou, Aikaterini
    Fisher, Helen L.
    Johnson, Sonia
    Major, Barnaby
    Rahaman, Nikola
    Chamberlain-Kent, Nick
    Stone, James M.
    EARLY INTERVENTION IN PSYCHIATRY, 2019, 13 (03) : 443 - 452
  • [40] A multisite Canadian study of outcome of first-episode psychosis treated in publicly funded early intervention services
    Malla, Ashok
    Schmitz, Norbert
    Norman, Ross
    Archie, Suzanne
    Windell, Deborah
    Roy, Paul
    Zipursky, Robert B.
    CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2007, 52 (09): : 563 - 571