Fluid Overload in a South African Pediatric Intensive Care Unit

被引：15

作者：

Ketharanathan, Naomi ^{[1
]}

McCulloch, Mignon ^{[2
,3
]}

Wilson, Clare ^{[4
]}

Rossouw, Beyra ^{[2
,3
]}

Salie, Shamiel ^{[2
,3
]}

Ahrens, Johan ^{[2
,3
]}

Morrow, Brenda M. ^{[2
,3
]}

Argent, Andrew C. ^{[2
,3
]}

机构：

[1] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Div Intens Care & Pediat Surg, Dept Pediat,Intens Care Unit, NL-3015 GJ Rotterdam, Netherlands

[2] Univ Cape Town, Dept Pediat Med, Div Pediat Crit Care & Childrens Heart Dis, ZA-7700 Cape Town, South Africa

[3] Red Cross War Mem Childrens Hosp, ZA-7700 Rondebosch, South Africa

[4] Univ London Imperial Coll Sci Technol & Med, Wright Fleming Inst, Wellcome Ctr Clin Trop Med, Dept Pediat, London W2 1PG, England

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2014年 / 60卷 / 06期

关键词：

fluid overload; pediatric; critical care; morbidity; mortality; CRITICALLY-ILL CHILDREN; ACUTE KIDNEY INJURY; SEPTIC SHOCK; OXYGENATION; INFANTS; BALANCE; UPDATE; RISK;

D O I：

10.1093/tropej/fmu041

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Objective: Fluid resuscitation is integral to resuscitation guidelines and critical care. However, fluid overload (FO) yields increased morbidity. Methods: Prospective observational study of Red Cross War Memorial Children's Hospital pediatric intensive care unit admissions (February to March 2013). FO % = (fluid in minus fluid out) [liters]/weight [kg] x 100%. Primary outcomes: FO >= 10%, 28 day mortality. Results: Median [interquartile range (IQR)] age: 9.5 (2.0-39.0) months, median (IQR) admission weight: 7.9 (3.6-13.7) kg. Median (IQR) FO with admission weight: 3.5 (2.1-4.9)%; three patients had FO >= 10%. The 28 day mortality was 10% (n = 10). Patients who died had higher mean (IQR) FO using admission weight [4.9 (2.9-9.3)% vs. 3.4 (1.9-4.8)%; p = 0.04]. Conclusions: Low FO >= 10% prevalence with 28 day mortality 10%. Higher FO% with admission weight associated with mortality (p = 0.04). We advocate further investigation of FO% as a simple bedside tool.

引用

页码：428 / 433

页数：6

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