Effects of rare earth elements on the growth of Cistanche deserticola cells and the production of phenylethanoid glycosides

被引:68
作者
Ouyang, J [1 ]
Wang, XD [1 ]
Zhao, B [1 ]
Yuan, XF [1 ]
Wang, YC [1 ]
机构
[1] Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100080, Peoples R China
关键词
Cistanche deserticola; cell growth; phenylethanoid glycosides; biosynthesis; rare earth elements;
D O I
10.1016/S0168-1656(03)00019-1
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The rare earth elements Nd, La, Ce at proper concentrations had positive effects on the cell growth of Cistanche deserticola and production of phenylethanoid glycosides (PeG). A mixture of rare earth elements (MRE, La2O3:CeO2:Pr6O11:Sm2O3 = 255:175:3: 1, mol/mol) showed the most remarkable effects. After 30 day's culture, 0.02 mmol l(-1) MRE gave the highest content (20.8%) and production (1.6 g l(-1)) of PeG, which were 104 and 167% higher than those obtained in control (without rare earth elements). (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:129 / 134
页数:6
相关论文
共 11 条
[1]  
Brown P.H., 1990, HDB PHYS CHEM RARE E, V13, P423, DOI [DOI 10.1016/S0168-1273(05)80135-7, 10.1016/S0168-1273(05)80135-7]
[2]  
DU NS, 1993, NAT PROD RES DEV, V3, P30
[3]  
DU NS, 1993, NAT PROD RES DEV, V4, P5
[4]   NUTRIENT REQUIREMENTS OF SUSPENSION CULTURES OF SOYBEAN ROOT CELLS [J].
GAMBORG, OL ;
MILLER, RA ;
OJIMA, K .
EXPERIMENTAL CELL RESEARCH, 1968, 50 (01) :151-+
[5]  
KOBAYASHI H, 1984, CHEM PHARM BULL, V32, P3009
[6]  
Li JC, 2001, J CHINA RARE EARTH S, V19, P162
[7]  
LI LL, 1997, CHINA J CHIN MAT MED, V22, P364
[8]  
MANN J, 1978, SECONDARY METABOLISM, P158
[9]  
NIE YX, 1989, J CHINA RARE EARTH S, V7, P58
[10]   Stimulation of taxol production and excretion in Taxus spp cell cultures by rare earth chemical lanthanum [J].
Wu, JY ;
Wang, CG ;
Mei, XG .
JOURNAL OF BIOTECHNOLOGY, 2001, 85 (01) :67-73