Renal ischemia-reperfusion injury: Renal dendritic cells loudly sound the alarm

被引：16
|
作者：
Nelson, P. J. [1 ]
机构：
[1] NYU, Sch Med, Div Nephrol, Smilow Res Ctr, New York, NY 10016 USA
来源：
KIDNEY INTERNATIONAL | 2007年 / 71卷 / 07期
关键词：
D O I：
10.1038/sj.ki.5002121
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Renal ischemia-reperfusion injury is a major cause of acute renal failure and kidney allograft dysfunction. Dong and colleagues now identify the surveying renal dendritic cell network as the predominant source of tumor necrosis factor-alpha during the early stages of renal ischemia reperfusion injury, raising the possibility for direct targeting of renal dendritic cells to help ameliorate this common form of renal injury and its sequelae.
引用
收藏
页码：604 / 605
页数：3
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