Wnts as morphogens?: The view from the wing of Drosophila

被引：46

作者：

Arias, AM ^{[1
]}

机构：

[1] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1038/nrm1078

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Morphogens are diffusible signalling molecules that pattern cellular fields by setting up differential gene expression in a concentration-dependent manner. Members of the Wnt family of signalling molecules are generally considered to be classical morphogens. However, a close analysis of their activity indicates that they do not fulfil all of the critera that are associated with the classical definition.

引用

页码：321 / 325

页数：5

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