Wnts as morphogens?: The view from the wing of Drosophila

被引：46
作者：
Arias, AM [1 ]
机构：
[1] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 04期
基金：
英国惠康基金;
关键词：
D O I：
10.1038/nrm1078
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Morphogens are diffusible signalling molecules that pattern cellular fields by setting up differential gene expression in a concentration-dependent manner. Members of the Wnt family of signalling molecules are generally considered to be classical morphogens. However, a close analysis of their activity indicates that they do not fulfil all of the critera that are associated with the classical definition.
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页码：321 / 325
页数：5
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