The utilization of traditional Chinese medicine in patients with dysfunctional uterine bleeding in Taiwan: a nationwide population-based study

被引：18
作者：
Lin, Yi-Rong [1 ]
Wu, Mei-Yao [2 ]
Chiang, Jen-Huai [3 ,4 ]
Yen, Hung-Rong [1 ,2 ,5 ,6 ,7 ]
Yang, Su-Tso [1 ,8 ]
机构：
[1] China Med Univ, Grad Inst Chinese Med, Sch Chinese Med, Coll Chinese Med, 91 Hsueh Shih Rd, Taichung 404, Taiwan
[2] China Med Univ Hosp, Dept Chinese Med, 2 Yude Rd, Taichung 404, Taiwan
[3] China Med Univ Hosp, Management Off Hlth Data, 2 Yude Rd, Taichung 404, Taiwan
[4] China Med Univ, Coll Med, Taichung 404, Taiwan
[5] China Med Univ, Res Ctr Chinese Herbal Med, Taichung 404, Taiwan
[6] Asia Univ, Dept Biotechnol, Taichung 41354, Taiwan
[7] China Med Univ Hosp, Dept Med Res, Res Ctr Tradit Chinese Med, 2 Yude Rd, Taichung 404, Taiwan
[8] China Med Univ Hosp, Dept Radiol, 2 Yude Rd, Taichung 404, Taiwan
来源：
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2017年 / 17卷
关键词：
Complementary and alternative medicine; Chinese herbal medicine; Dysfunctional uterine bleeding; National Health Insurance Research Database; Traditional Chinese medicine; MICE; SAN; PRESCRIPTION; DYSMENORRHEA; SCM-198; PATTERNS; PATHWAY; STRESS; MODEL; RAT;
D O I：
10.1186/s12906-017-1939-1
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Background: Many patients with gynecological disorders seek traditional medicine consultations in Asian countries. This study intended to investigate the utilization of traditional Chinese medicine (TCM) in patients with dysfunctional uterine bleeding (DUB) in Taiwan. Methods: We analyzed a cohort of one million individuals randomly selected from the National Health Insurance Research Database in Taiwan. We included 46,337 subjects with newly diagnosed DUB (ICD-9-CM codes 626.8) from January 1, 1997 to December 31, 2010. The patients were categorized into TCM seekers and non-TCM seekers according to their use of TCM. Results: Among the subjects, 41,558 (89.69%) were TCM seekers and 4,779 (10.31%) were non-TCM seekers. Patients who were younger tended to be TCM seekers. Most of the patients had also taken Western medicine, especially tranexamic acid and non- steroidal anti-inflammatory drugs (NSAIDs). More than half of TCM seekers (55.41%) received combined treatment with both Chinese herbal remedies and acupuncture. The most commonly used TCM formula and single herb were Jia-Wei-Xiao-Yao-San (Bupleurum and Peony Formula) and Yi-Mu-Cao (Herba Leonuri), respectively. The core pattern of Chinese herbal medicine for DUB patients consisted of Jia-Wei-Xiao-Yao-San, Xiang-Fu (Rhizoma Cyperi), and Yi-Mu-Cao (Herba Leonuri). Conclusions: TCM use is popular among patients with DUB in Taiwan. Further pharmacological investigations and clinical trials are required to validate the efficacy and safety of these items.
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页数：12
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