Studies on Polyethers Produced by Red Algae

被引：25

作者：

Cen-Pacheco, Francisco ^{[1
]}

Nordstroem, Laurette ^{[1
]}

Luisa Souto, Maria ^{[1
]}

Norte Martin, Manuel ^{[1
]}

Javier Fernandez, Jose ^{[1
]}

Hernandez Daranas, Antonio ^{[1
,2
]}

机构：

[1] Univ La Laguna, Inst Univ Bioorgan Antonio Gonzalez, E-38206 Tenerife, Spain

[2] Univ La Laguna, Dept Ingn Quim & Tecnol Farmaceut, Tenerife 38071, Spain

来源：

MARINE DRUGS | 2010年 / 8卷 / 04期

关键词：

polyether; marine compound; triterpene; Laurencia viridis; SQUALENE-DERIVED TRITERPENES;

D O I：

10.3390/md8041178

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two novel squalene-derived triterpenes, spirodehydrovenustatriol (3) and 14-keto-dehydrothyrsiferol (4) were isolated from the red alga Laurencia viridis, together with two new and unusual C-17 terpenoids, adejen A (5) and B (6). These truncated structures possess structural similarities with other known squalene metabolites and their biogenetic origin has been proposed on the basis of an oxidative process of the squalene skeleton. All the structures were elucidated by extensive use of 2D NMR spectroscopic methods.

引用

页码：1178 / 1188

页数：11

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