Computational modeling of arterial biomechanics: Insights into pathogenesis and treatment of vascular disease

被引:57
作者
Steinman, DA
Vorp, DA
Ethier, CR [1 ]
机构
[1] Univ Toronto, Dept Mech & Ind Engn, Toronto, ON M5S 3G8, Canada
[2] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G8, Canada
[3] Univ Western Ontario, Imaging Res Labs, Robarts Res Inst, London, ON, Canada
[4] Univ Western Ontario, Dept Med Biophys, London, ON, Canada
[5] Univ Western Ontario, Dept Diagnost Radiol, London, ON, Canada
[6] Univ Pittsburgh, Dept Surg, Pittsburgh, PA USA
[7] Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA USA
[8] Univ Pittsburgh, McGowan Inst Regenerat Med, Pittsburgh, PA USA
关键词
D O I
10.1067/mva.2003.122
中图分类号
R61 [外科手术学];
学科分类号
摘要
We review how advances in computational techniques are improving our understanding of the biomechanical behavior of the healthy and diseased cardiovascular system. Numerical modeling of biomechanics is being used in a wide variety of ways, including assessment of effects of mural and hemodynamically induced stresses on atherogenesis, development of risk measures for aneurysm rupture, improvement in interpretation of medical images, and quantification of oxygen transport in diseased and healthy arteries. Although not amenable to routine clinical use, numerical modeling of cardiovascular biomechanics is a powerful research tool.
引用
收藏
页码:1118 / 1128
页数:11
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