Synthesis of difluorinated cyclopropanoid nucleoside analogues

被引：0

作者：

Csuk, R ^{[1
]}

Thiede, G ^{[1
]}

机构：

[1] Univ Halle Wittenberg, Inst Organ Chem, D-06120 Halle Saale, Germany

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2002年 / 57卷 / 11期

关键词：

nucleoside analogues; cyclopropanes; HPLC;

D O I：

暂无

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Starting from (2,2-difluorocyclopropyl)methanol a novel class of difluorinated cyclopropanoid nucleoside analogues containing two hydroxymethyl side chains was synthesized in a straightforward way. Several of the final compounds could be obtained in an enantiomerically pure form by HPLC using chiral stationary phases.

引用

页码：1287 / 1294

页数：8

共 25 条

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