Self-assembling peptide-based hydrogels: Fabrication, properties, and applications

被引：66
作者：
Fu, Kun [1 ]
Wu, Hanguang [2 ]
Su, Zhiqiang [1 ]
机构：
[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing Key Lab Adv Funct Polymer Composites, Beijing 100029, Peoples R China
[2] Beijing Inst Fash Technol, Beijing Key Lab Clothing Mat R&D Assessment, Beijing 100029, Peoples R China
来源：
BIOTECHNOLOGY ADVANCES | 2021年 / 49卷
基金：
中国国家自然科学基金;
关键词：
Peptide-based hydrogel; Self-assembling; Rheology; Biocompatibility; Biological application; SUPRAMOLECULAR HYDROGEL; NANOFIBER HYDROGELS; AMPHIPHILE NANOFIBERS; MULTIDOMAIN PEPTIDES; ENZYMATIC FORMATION; DELIVERY; DESIGN; PH; HYDROPHOBICITY; ANGIOGENESIS;
D O I：
10.1016/j.biotechadv.2021.107752
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The hierarchical formation of self-assembling peptide-based hydrogels (SAPHs) starts from peptide to nanofibers, following with the entanglement into hydrogels with nanofibrous network. Such characteristic structure and extraordinary biocompatibility, and the peptide components endow the SAPHs with diverse applications in biotechnological field. Therefore, the thorough comprehension of SAPHs is significant to broadening their application. In this review, fabrication, properties, and biological applications of the SAPHs are introduced, and the factors influencing the synthesis process as well as the properties of the SAPHs products are also systematically explained. Meanwhile, we conclude the problems to be solved and provide our perspective to the future development of SAPHs in the biotechnology.
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收藏
页数：17
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