A comparative pathological finding in pigs exposed to fumonisin B I and/or Mycoplasma hyopneumoniae

被引：13

作者：

Posa, Roland ^{[1
]}

Stoev, Stoycho ^{[2
]}

Kovacs, Melinda ^{[1
,3
,4
]}

Donko, Tamas ^{[1
]}

Repa, Imre ^{[1
]}

Magyar, Tibor ^{[5
]}

机构：

[1] Kaposvar Univ, Fac Anim Sci, Kaposvar, Hungary

[2] Trakia Univ, Fac Vet Med, Dept Gen & Clin Pathol, Stara Zagora 6000, Bulgaria

[3] Hungarian Acad Sci, Res Grp Mycotoxins Food Chain, H-1051 Budapest, Hungary

[4] Kaposvar Univ, Budapest, Hungary

[5] Hungarian Acad Sci, Vet Med Res Inst, Agr Res Ctr, H-1581 Budapest, Hungary

来源：

TOXICOLOGY AND INDUSTRIAL HEALTH | 2016年 / 32卷 / 06期

基金：

匈牙利科学研究基金会;

关键词：

Fumonisin B-1; Mycoplasma hyopneumoniae; computed tomography; pathology; pigs; PASTEURELLA-MULTOCIDA; B-1; ALTERS; MYCOTOXINS; SWINE; CONTAMINATION; PNEUMONIA; INFECTION; VIRUS; SUSCEPTIBILITY; EPIDEMIOLOGY;

D O I：

10.1177/0748233714543735

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A more complicated pathology was observed in female pigs infected with Mycoplasma hyopneumoniae, when the same were exposed to 20 ppm dietary levels of fumonisin B1 (FBI) starting 14 days before infection for a period of 42 days as was assessed by gross pathology and pathomorphological examinations or computed tomography, and also manifested by the strong deterioration of the pneumonic process in two pigs and the subsequent euthanizing of one pig. Typical damages in FBI -fed pigs were a strong oedema in the lung and slight oedema in the other internal organs and mild degenerative changes in the kidneys, whereas the typical pathomorphological changes in M. hyopneumoniae-infected pigs corresponded to the morphologic pattern of a catarrhal bronchointerstitial pneumonia more pronounced in the cranial and middle lobes or in the cranial third of the caudal lobe of the lung. The pigs treated by both pathogens (toxic and infectious) revealed strong oedematous changes in the interstitium of lung in addition to deteriorated and extended bronchointerstitial pneumonic process.

引用

页码：998 / 1012

页数：15

共 65 条

[1] Cytotoxicity of fumonisin B1:: implication of lipid peroxidation and inhibition of protein and DNA syntheses [J].