A self-assembled DNA nanostructure as a FRET nanoflare for intracellular ATP imaging

被引：15

作者：

Cai, Shijun ^{[1
]}

Wang, Jiaoli ^{[1
]}

Li, Jing ^{[1
]}

Zhou, Bing ^{[1
]}

He, Chunmei ^{[1
]}

Meng, Xiangxian ^{[1
]}

Huang, Jin ^{[1
]}

Wang, Kemin ^{[1
]}

机构：

[1] Hunan Univ, Coll Biol, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr,Key La, Changsha, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 51期

基金：

中国国家自然科学基金;

关键词：

MESSENGER-RNA DETECTION; MOLECULAR BEACON; SWITCHING DNA; APTAMER; NANOFLOWERS; MICRORNAS; ADENOSINE; FLARES; DEVICE;

D O I：

10.1039/d1cc02316k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Due to the incorporation of gold nanoparticles (AuNPs), previously reported AuNP-based FRET nanoflares still have some problems, such as non-negligible cytotoxicity and a time-consuming preparation procedure. In this communication, a novel AuNP-free FRET nanoflare for intracellular ATP imaging is developed based on a DNA nanostructure, which is self-assembled through cyclic U-type hybridization only involving a certain number of DNA strands.

引用

收藏

页码：6257 / 6260

页数：4

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