Comparison of Curative Effects between Minimally Invasive Percutaneous Lag Screw Internal Fixation and Reconstruction Plate for Unstable Pelvic Fractures

Objective: To compare the clinical efficacy of minimally invasive percutaneous lag screw internal fixation and reconstruction plate in the treatment of unstable pelvic fractures. Study Design: An experimental study. Place and Duration of Study: The Department of Orthopaedics, Second People's Hospital of Liaocheng, Linqing City, China, from January 2016 to March 2018. Methodology: A total of 130 patients with unstable pelvic fracture were randomly divided into group A and group B, with 65 cases in each group. Group A was treated with minimally invasive percutaneous lag screw internal fixation, and group B was treated with reconstruction plate. Clinical efficacy of two groups after treatment was evaluated. Serum alkaline phosphatase (ALP), tumor necrosis factor-alpha (TNF-alpha), C-reactive protein (CRP), stress hormones cortisol (Cor), angiotensin II (Ang II), and norepinephrine (NE) contents were compared. Results: After treatment, the excellent and good rate in group Awas higher than that in group B (p=0.005). At 7 days after the operation, serum ALP level in group Awas higher than that in group B (p <0.001), serum TNF-alpha, CRP, Cor, Ang II, and NE levels were lower in group A than those in group B (all p <0.001). Conclusion: Compared with reconstruction plate, minimally invasive percutaneous lag screw internal fixation has better clinical efficacy in patients with unstable pelvic fractures; meanwhile, it can effectively increase serum ALP level, reduce the levels of inflammatory cytokines TNF-alpha and CRP, and effectively reduce surgical trauma as well as postoperative body stress response.