Epstein-Barr virus DNA in the cerebrospinal fluid of an HIV patient with primary cerebral lymphoma

被引：4
作者：
Plebani, A
Pinzani, R
Vago, L
Cinque, P
Triulzi, F
Zibordi, F
Angelini, L
机构：
[1] Univ Milan, HIV Paediat Ctr, I-20122 Milan, Italy
[2] Univ Milan, Osped L Sacco, Pathol Unit, I-20157 Milan, Italy
[3] Hosp San Raffaele, IRCCS, Dept Neuroradiol, I-20132 Milan, Italy
[4] Hosp San Raffaele, IRCCS, Dept Infect Dis, I-20127 Milan, Italy
[5] Ist Nazl Neurol C Besta, Dept Neuropaediat, I-20133 Milan, Italy
来源：
EUROPEAN JOURNAL OF PEDIATRICS | 1998年 / 157卷 / 04期
关键词：
Epstein-Barr virus DNA; human immunodeficiency virus; polymerase chain reaction; primary cerebral lymphoma;
D O I：
10.1007/s004310050813
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The case of a 7-month-old boy with vertically acquired immunodeficiency syndrome and multifocal primary cerebral lymphoma is reported. Neither neurological nor neuroradiological findings contributed towards the appropriate diagnosis. Positive Epstein-Barr virus DNA, assessed by means of polymerase chain reaction in cerebrospinal fluid, strongly suggested a diagnosis of primary cerebral lymphoma, which was subsequently confirmed by autopsy. Conclusions The detection of Epstein-Barr virus DNA using the polymerase chain reaction in cerebrospinal fluid is useful for the diagnosis of primary cerebral lymphoma.
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收藏
页码：291 / 293
页数：3
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