Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project

被引：54

作者：

Mahajan, Shiwani ^{[1
,2
,3
,4
]}

Zhang, Danwei ^{[1
]}

He, Siyun ^{[1
,2
,3
,5
]}

Lu, Yuan ^{[1
,2
,3
]}

Gupta, Aakriti ^{[1
,2
,3
,6
]}

Spatz, Erica S. ^{[1
,2
,3
,4
]}

Lu, Jiapeng ^{[1
]}

Huang, Chenxi ^{[1
,2
,3
]}

Herrin, Jeph ^{[4
]}

Liu, Shuling ^{[1
,2
,3
]}

Yang, Jingwei ^{[1
]}

Wu, Chaoqun ^{[1
]}

Cui, Jianlan ^{[1
]}

Zhang, Qiuli ^{[1
]}

Li, Xi ^{[1
,2
]}

Nasir, Khurram ^{[1
,2
,3
,4
]}

Zheng, Xin ^{[1
,2
]}

Krumholz, Harlan M. ^{[1
,2
,3
,4
,7
]}

Li, Jing ^{[1
,2
]}

Huang, Chun ^{[1
,2
,3
,8
]}

Dong, Zhong ^{[8
]}

Jiang, Bo ^{[8
]}

Guo, Zhigang ^{[9
]}

Zhang, Ying Yi ^{[9
]}

Sun, Jixin ^{[10
]}

Liu, Yuhuan ^{[1
,2
,3
,10
]}

Ren, Zeping ^{[11
]}

Meng, Yaqing ^{[11
]}

Wang, Zhifen ^{[12
]}

Xi, Yunfeng ^{[12
]}

Xing, Liying ^{[13
]}

Tian, Yuanmeng ^{[13
]}

Liu, Jianwei ^{[14
]}

Fu, Yao ^{[14
]}

Liu, Ting ^{[14
]}

Sun, Wei ^{[15
]}

Yan, Shichun ^{[15
]}

Jin, Lin ^{[15
]}

Zheng, Yang ^{[16
]}

Wang, Jing ^{[16
]}

Yan, Jing ^{[1
,17
,18
]}

Xu, Xiaoling ^{[17
,18
]}

Chen, Yeji ^{[19
]}

Xing, Xiuya ^{[19
]}

Zhang, Luan ^{[19
]}

Zhong, Wenling ^{[20
]}

Fang, Xin ^{[20
]}

Zhu, Liping ^{[21
]}

Xu, Yan ^{[21
]}

Guo, Xiaolei ^{[22
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, NHC Key Lab Clin Res Cardiovasc Medicat, Natl Clin Res Ctr Cardiovasc Dis, Natl Ctr Cardiovasc Dis,Fuwai Hosp, Beijing, Peoples R China

[2] Natl Ctr Cardiovasc Dis, Cent China Subctr, Zhengzhou, Henan, Peoples R China

[3] Yale New Haven Hosp, Ctr Outcomes Res & Evaluat, 20 York St, New Haven, CT 06504 USA

[4] Yale Sch Med, Dept Internal Med, Sect Cardiovasc Med, New Haven, CT USA

[5] Yale Univ, Sch Publ Hlth, Dept Biostat, New Haven, CT USA

[6] Columbia Univ, Sect Cardiovasc Med, New York, NY USA

[7] Yale Sch Publ Hlth, Dept Hlth Policy & Management, New Haven, CT USA

[8] Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China

[9] Tianjin Chest Hosp, Tianjin, Peoples R China

[10] Hebei Ctr Dis Prevent & Control, Shijiazhuang, Hebei, Peoples R China

[11] Shanxi Ctr Dis Prevent & Control, Taiyuan, Shanxi, Peoples R China

[12] Inner Mongolia Ctr Dis Prevent & Control, Hohhot, Peoples R China

[13] Liaoning Ctr Dis Prevent & Control, Shenyang, Liaoning, Peoples R China

[14] Jilin Ctr Dis Prevent & Control, Jilin, Jilin, Peoples R China

[15] Heilongjiang Ctr Dis Prevent & Control, Harbin, Heilongjiang, Peoples R China

[16] Shanghai Ctr Dis Prevent & Control, Shanghai, Peoples R China

[17] Jiangsu Ctr Dis Prevent & Control, Nanjing, Jiangsu, Peoples R China

[18] Provincial Peoples Hospital:, Guangzhou, Guangdong, Peoples R China

[19] Anhui Ctr Dis Prevent & Control, Hefei, Anhui, Peoples R China

[20] Fujian Ctr Dis Prevent & Control, Fuzhou, Fujian, Peoples R China

[21] Jiangxi Ctr Dis Prevent & Control, Nanchang, Jiangxi, Peoples R China

[22] Shandong Ctr Dis Prevent & Control, Jinan, Shandong, Peoples R China

[23] Henan Ctr Dis Prevent & Control, Zhengzhou, Henan, Peoples R China

[24] Hubei Ctr Dis Prevent & Control, Wuhan, Hubei, Peoples R China

[25] Hunan Ctr Dis Prevent & Control, Changsha, Hunan, Peoples R China

[26] Guangdong Prov Peoples Hosp, Guangzhou, Guangdong, Peoples R China

[27] Guangxi Med Univ, Affiliated Hosp 1, Nanning, Peoples R China

[28] Hlth Commiss Hainan, Haikou, Hainan, Peoples R China

[29] Hainan Ctr Dis Prevent & Control, Haikou, Hainan, Peoples R China

[30] Chongqing Ctr Dis Prevent & Control, Chongqing, Peoples R China

[31] Sichuan Ctr Dis Prevent & Control, Chengdu, Sichuan, Peoples R China

[32] Guizhou Prov Peoples Hosp, Guiyang, Guizhou, Peoples R China

[33] Yunnan Ctr Dis Prevent & Control, Kunming, Yunnan, Peoples R China

[34] Tibet Ctr Dis Prevent & Control, Lhasa, Peoples R China

[35] Shaanxi Ctr Dis Prevent & Control, Taiyuan, Shanxi, Peoples R China

[36] Gansu Ctr Dis Prevent & Control, Lanzhou, Gansu, Peoples R China

[37] Qinghai Ctr Dis Prevent & Control, Beijing, Peoples R China

[38] Ningxia Ctr Dis Prevent & Control, Ningxia, Peoples R China

[39] Xinjiang Med Univ, Affiliated Hosp 1, Urumqi, Peoples R China

[40] Xinjiang Corps Ctr Dis Prevention & Control, Urumqi, Peoples R China

来源：

JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2019年 / 8卷 / 19期

关键词：

awareness; hypertension subtypes; isolated diastolic hypertension; prevalence; treatment; ISOLATED SYSTOLIC HYPERTENSION; INCIDENT HEART-FAILURE; 10-YEAR FOLLOW-UP; BLOOD-PRESSURE; RISK-FACTORS; CARDIOVASCULAR-DISEASE; SUBTYPES; ADULTS; ASSOCIATION; YOUNG;

D O I：

10.1161/JAHA.119.012954

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background-Characterizing and assessing the prevalence, awareness, and treatment patterns of patients with isolated diastolic hypertension (IDH) can generate new knowledge and highlight opportunities to improve their care. Methods and Results-We used data from the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Million Persons Project, which screened 2 351 035 participants aged 35 to 75 years between 2014 and 2018. IDH was defined as systolic and diastolic blood pressure of <140 and >= 90 mm Hg; awareness as self-reported diagnosis of hypertension; and treatment as current use of antihypertensive medications. Of the 2 310 184 participants included (mean age 55.7 years; 59.5% women); 73 279 (3.2%) had IDH, of whom 63 112 (86.1%) were untreated, and only 6512 (10.3%) of the untreated were aware of having hypertension. When compared with normotensives, participants who were <60 years, men, at least college educated, had body mass index of >28 kg/m(2), consumed alcohol, had diabetes mellitus, and prior cardiovascular events were more likely to have IDH (all P<0.01). Among those with IDH, higher likelihood of awareness was associated with increased age, women, college education, body mass index of >28 kg/m(2), higher income, diabetes mellitus, prior cardiovascular events, and Central or Eastern region (all P<0.05). Most treated participants with IDH reported taking only 1 class of antihypertensive medication. Conclusions-IDH affects a substantial number of people in China, however, few are aware of having hypertension and most treated participants are poorly managed, which suggests the need to improve the diagnosis and treatment of people with IDH.

引用

页数：29

共 33 条

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