Postoperative Analgesic Efficacy of Preemptive and Postoperative Lornoxicam or Tramadol in Lumbar Disc Surgery

被引:2
作者
Coskun, Esma [1 ]
Dincer, Emine [2 ]
Turan, Guldem [3 ]
Ozgultekin, Asu [2 ]
机构
[1] Private Mozaik Hosp, Dept Anaesthesiol & Reanimat, Antakya, Turkey
[2] Haydarpasa Numune Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
[3] Fatih Sultan Mehmet Training & Res Hosp, Clin Anaesthesiol & Reanimat, Istanbul, Turkey
关键词
Analgesia; lornoxicam; lumbar disc surgery; tramadol; PAIN-CONTROL; DOUBLE-BLIND; PREOPERATIVE LORNOXICAM; PREVENTIVE ANALGESIA; RANDOMIZED-TRIAL; TONSILLECTOMY; TOLERABILITY; PHARMACOLOGY; MORPHINE; SAFETY;
D O I
10.5152/TJAR.2019.60963
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objective: To compare preemptive and postoperative analgesic efficacy of tramadol and lornoxicam administered before anaesthesia induction in lumbar discectomy. Methods: This randomised, double-blind trial was conducted on 60 ASA I and II patients undergoing lumbar discectomy. Group L (n=30) received 3x8 mg day(-1) lornoxicam, and Group T (n=30) received 3x1.5 mg kg(-1) day(-1) tramadol. A verbal rating scale (VRS), the duration of effective analgesia, the number of additional analgesics used, adverse effects and patient satisfaction were evaluated at the postoperative 30th minute and 1st, 2nd, 4th, 6th, 8th, 12th and 24th hours. Results: There were no significant differences between Groups L and T regarding demographic and clinical characteristics, the number of additional analgesics and the duration of effective analgesia, adverse effects and patient satisfaction. VRS scores of the patients in Group T were significantly higher than those in Group L at the postoperative 30th minute (p=0.050) and the 1st hour (p=0.005). Conclusion: Lornoxicam, which was used for preemptive and postoperative analgesia in lumbar disc surgery, had provided adequate and effective analgesia such as tramadol. Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.
引用
收藏
页码:375 / 381
页数:7
相关论文
共 50 条
  • [21] Efficacy of Tramadol as a Sole Analgesic for Postoperative Pain in Male and Female Mice
    Wolfe, A. Marissa
    Kennedy, Lucy H.
    Na, Jane J.
    Nemzek-Hamlin, Jean A.
    JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 2015, 54 (04): : 411 - 419
  • [22] Postoperative pain therapy after lumbar disc surgery
    Filippi, R
    Laun, J
    Jage, J
    Perneczky, A
    ACTA NEUROCHIRURGICA, 1999, 141 (06) : 613 - 618
  • [23] Effects of preoperative lornoxicam versus tramadol on postoperative pain and adverse effects in adult tonsillectomy patients
    Isik, Berrin
    Arslan, Mustafa
    Ozsoylar, Ozgur
    Akcabay, Mehmet
    AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY, 2009, 21 (03): : 113 - 120
  • [24] The postoperative analgesic efficacy of intraperitoneal tramadol compared to normal saline or intravenous tramadol in laparoscopic cholecystectomy
    Akinci, S. B.
    Ayhan, B.
    Aycan, I. O.
    Tirnaksiz, B.
    Basgul, E.
    Abbasoglu, O.
    Aypar, U.
    Sayek, I.
    EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2008, 25 (05) : 375 - 381
  • [25] Effects of postoperative analgesia with the combination of tramadol and lornoxicam on serum inflammatory cytokines in patients with gastric cancer
    Sun, He Liang
    Dong, Ying Chun
    Wang, Can Qin
    Qian, Yan Ning
    Wang, Zhong Yun
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2014, 52 (12) : 1023 - 1029
  • [26] Effects of peroperative intravenous paracetamol and lornoxicam for lumbar disc surgery on postoperative pain and opioid consumption: A randomized, prospective, placebo-controlled study
    Bilir, Serhat
    Yurtlu, Bulent Serhan
    Hanci, Volkan
    Okyay, Rahsan Dilek
    Kayhan, Gulay Erdogan
    Ayoglu, Hilal Peri
    Ozkocakturan, Isil
    AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY, 2016, 28 (02): : 98 - 105
  • [27] Postoperative pain management after inguinal hernia repair: lornoxicam versus tramadol
    O. Mentes
    M. Bagci
    Hernia, 2009, 13
  • [28] Effects of Preemptive Intravenous Lornoxicam on the Analgesic Efficacy of Epidural Morphine and Expression of Chemokines in Women Undergoing Hysterectomy
    Tang, Qi-Feng
    Qian, Yan-Ning
    Qiu, Yu-Hua
    Yang, Jian-Jun
    Wang, Zhong-Yun
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 2009, 70 (01): : 1 - 9
  • [29] A Comparative Study of the Efficacy of IV Dexketoprofen, Lornoxicam, and Diclophenac Sodium on Postoperative Analgesia and Tramadol Consumption in Patients Receiving Patient-Controlled Tramadol
    Kilickaya, Refika
    Gulec, Ersel
    Unlugenc, Hakki
    Gunduz, Murat
    Isik, Geylan
    TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, 2015, 43 (03) : 174 - 180
  • [30] Efficacy of Oral Toradol (Ketorolac) Compared to Oral Tramadol as a Preemptive Analgesic in Impacted Third Molar Surgery
    Rao, Ufaq
    Fazal, Mohsin
    JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2023, 33 (08): : 895 - 899