Synthesis of a new poly([R]-3-hydroxybutyrate) RAFT agent

被引：26

作者：

Jiang, Lu ^{[1
]}

Liow, Sing Shy ^{[1
]}

Loh, Xian Jun ^{[1
,2
,3
]}

机构：

[1] ASTAR, Inst Mat Res & Engn, 2 Fusionopolis Way,08-03 Innovis, Singapore 138634, Singapore

[2] Natl Univ Singapore, Dept Mat Sci & Engn, 9 Engn Dr 1, Singapore 117576, Singapore

[3] Singapore Eye Res Inst, 11 Third Hosp Ave, Singapore 168751, Singapore

来源：

POLYMER CHEMISTRY | 2016年 / 7卷 / 09期

关键词：

POLY(ESTER URETHANE)S; POLY(ETHYLENE GLYCOL); TRANSESTERIFICATION KINETICS; COPOLYMERS; POLYMERIZATION; POLY(3-HYDROXYBUTYRATE); BIODIESEL; GELATION; OIL;

D O I：

10.1039/c5py01812a

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly[(R)-3-hydroxybutyrate] (PHB) has attracted more and more attention in biomedical applications in recent years, due to its excellent properties of sustainability, biodegradability and biocompatibility. In this work, purified natural PHB was modified by 1-hexanol through transesterification reaction to form mono-hydroxylated PHB. The kinetic process of transesterification was carefully investigated. The mono-hydroxylated PHB was reacted with the thiocarbonylthio compound to generate a biodegradable macro mono-hydroxylated PHB chain transfer agent (CTA), which could react with other monomers to produce block copolymers. The monomer, 2-dimethylaminoethyl methacrylate (DMAEMA) was chosen to demonstrate the copolymerization process and the block copolymer PHB-b-PDMAEMA was obtained.

引用

页码：1693 / 1700

页数：8

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