Neurotological complications after radiosurgery versus conservative management in acoustic neuromas: A systematic review-based study

被引:21
作者
Shin, YJ
Lapeyre-Mestre, M
Gafsi, I
Cognard, C
Deguine, O
Tremoulet, M
Fraysse, B
机构
[1] Hosp Purpan, Serv ORL, Dept Otolaryngol, FR-31059 Toulouse, France
[2] Univ Toulouse 3, Fac Med Toulouse Purpan, Dept Clin Pharmacol, F-31062 Toulouse, France
[3] Purpan Hosp, Dept Neuroradiol, Toulouse, France
[4] Purpan Hosp, Dept Neurosurg, Toulouse, France
关键词
acoustic neuroma; conservative management; facial neuralgia; facial palsy; gamma-knife surgery; hearing loss; hydrocephalus; radiosurgery;
D O I
10.1081/0036554021000028084
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective-Treatment modalities for acoustic neuroma (AN) include surgery, observation and gamma-knife surgery. The aim of this study was to compare neurotological complications resulting from two treatment alternatives to microsurgery: radiosurgery and observation. Material and methods-We conducted a systematic review of the literature dealing with radiosurgery for AN and compared the rate of neurotological complications in this population with that in a cohort of patients managed conservatively. Results-We found that neurotological complications, namely facial hypoesthesia (p = 0.002), hearing loss (p < 0.05) and hydrocephalus (p = 0.02), were more frequently encountered after radiosurgery than with conservative management. In contrast, we found that the risk of growth of AN is significantly higher with conservative management and that the rate of stability of the tumor did not differ significantly between the two treatments. Conclusion-We prefer a conservative management regimen for patients who cannot be operated on for their AN. However, there are some difficulties inherent in this conservative management policy, namely non-compliance and difficulties in establishing the evolution of the tumor.
引用
收藏
页码:59 / 64
页数:6
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