Solid pseudopapillary tumor of the pancreas with liver metastasis: Clinical features and management

Objective: To summarize the diagnosis and management of metastatic pancreatic solid pseudopapillary tumors (SPTs). Methods: We retrospectively analyzed the clinical data of patients with metastatic pancreatic SPTs who were admitted to Peking Union Medical College Hospital from November 2001 to September 2013. Results: A total of 187 patients with pancreatic SPTs were admitted. Four patients had liver metastasis, and all four were female patients aged 20-72 years old. Each patient with metastases underwent surgical resection with good postoperative recovery. The mean follow-up period was 30 months (range, 1-64 months). None of the patients had obvious recurrence or distant metastasis. Conclusions: Pancreatic SPT with liver metastasis is very rare, and surgical resection is an effective treatment option. The principle of surgical treatment is to resect the primary and metastatic lesions as completely as possible. The affected patients require long-term postoperative follow-up. (C) 2014 Elsevier Ltd. All rights reserved.