Magnetic resonance parkinsonism index in progressive supranuclear palsy and vascular parkinsonism

被引：31

作者：

Mostile, Giovanni ^{[1
]}

Nicoletti, Alessandra ^{[1
]}

Cicero, Calogero Edoardo ^{[1
]}

Cavallaro, Tiziana ^{[1
]}

Bruno, Elisa ^{[1
]}

Dibilio, Valeria ^{[1
]}

Luca, Antonina ^{[1
]}

Sciacca, Giorgia ^{[1
]}

Raciti, Loredana ^{[1
]}

Contrafatto, Donatella ^{[1
]}

Chiaramonte, Ignazio ^{[1
]}

Zappia, Mario ^{[1
]}

机构：

[1] Univ Catania, Sez Neurosci, Dipartimento GF Ingrassia, Via S Sofia 78, I-95123 Catania, Italy

来源：

NEUROLOGICAL SCIENCES | 2016年 / 37卷 / 04期

关键词：

Progressive supranuclear palsy; Vascular parkinsonism; Magnetic resonance imaging morphometry; Magnetic resonance parkinsonism index; MULTIPLE SYSTEM ATROPHY; DIAGNOSIS; DIFFERENTIATION; CRITERIA; DISEASE;

D O I：

10.1007/s10072-016-2489-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To investigate accuracy of the magnetic resonance parkinsonism index (MRPI) in differentiating progressive supranuclear palsy (PSP) from vascular parkinsonism (VP). We retrospectively analyzed radiological data of 12 PSP patients and 17 VP patients group-matched by age and sex who performed a standardized brain magnetic resonance imaging (MRI). Analysis of selected structures morphometry was performed to all study subjects and the MRPI was calculated for each selected patient. MRI midbrain area as well as superior cerebellar peduncle width were significantly lower in PSP patients compared to VP subjects. MRPI was significantly larger in PSP patients compared to VP subjects. MRPI value a parts per thousand yen13 distinguished the two groups with a sensitivity of 100 % (95 % CI 69.9-100) and a specificity of 100 % (95 % CI 77.1-100). MRPI may represent an accurate tool in differentiating PSP from VP.

引用

收藏

页码：591 / 595

页数：5

相关论文

共 15 条

[1] Relationship between brainstem MRI and pathological findings in progressive supranuclear palsy - study in autopsy cases [J].

Aiba, I ;

Hashizume, Y ;

Yoshida, M ;

Okuda, S ;

Murakami, N ;

Ujihira, N .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1997, 152 (02) :210-217

[2] PROGRESSIVE SUPRANUCLEAR PALSY AND A MULTIINFARCT STATE [J].

DUBINSKY, RM ;

JANKOVIC, J .

NEUROLOGY, 1987, 37 (04) :570-576

[3] A clinicopathological study of vascular progressive supranuclear palsy - A multi-infarct disorder presenting as progressive supranuclear palsy [J].

Josephs, KA ;

Ishizawa, T ;

Tsuboi, Y ;

Cookson, N ;

Dickson, DW .

ARCHIVES OF NEUROLOGY, 2002, 59 (10) :1597-1601

[4] Infratentorial abnormalities in vascular dementia [J].

Leite, AJB ;

van der Flier, WM ;

van Straaten, ECW ;

Scheltens, P ;

Barkhof, F .

STROKE, 2006, 37 (01) :105-110

[5] Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): Report of the NINDS-SPSP International Workshop [J].

Litvan, I ;

Agid, Y ;

Calne, D ;

Campbell, G ;

Dubois, B ;

Duvoisin, RC ;

Goetz, CG ;

Golbe, LI ;

Grafman, J ;

Growdon, JH ;

Hallett, M ;

Jankovic, J ;

Quinn, NP ;

Tolosa, E ;

Zee, DS ;

Chase, TN ;

FitzGibbon, EJ ;

Hall, Z ;

Juncos, J ;

Nelson, KB ;

Oliver, E ;

Pramstaller, P ;

Reich, SG ;

Verny, M .

NEUROLOGY, 1996, 47 (01) :1-9

[6] Accuracy of Magnetic Resonance Parkinsonism Index for Differentiation of Progressive Supranuclear Palsy from Probable or Possible Parkinson Disease [J].

Morelli, Maurizio ;

Arabia, Gennarina ;

Salsone, Maria ;

Novellino, Fabiana ;

Giofre, Laura ;

Paletta, Rosina ;

Messina, Demetrio ;

Nicoletti, Giuseppe ;

Condino, Francesca ;

Gallo, Olivier ;

Lanza, Pierluigi ;

Quattrone, Aldo .

MOVEMENT DISORDERS, 2011, 26 (03) :527-533

[7] MR imaging of middle cerebellar peduncle width: Differentiation of multiple system atrophy from Parkinson disease [J].

Nicoletti, Giuseppe ;

Fera, Francesco ;

Condino, Francesca ;

Auteri, William ;

Gallo, Olivier ;

Pugliese, Pierfrancesco ;

Arabia, Gennarina ;

Morgante, Letterio ;

Barone, Paolo ;

Zappia, Mario ;

Quattrone, Aldo .

RADIOLOGY, 2006, 239 (03) :825-830

[8] MR imaging index for differentiation of progressive supranuclear palsy from Parkinson disease and the Parkinson variant of multiple system atrophy [J].

Quattrone, Aldo ;

Nicoletti, Giuseppe ;

Messina, Demetrio ;

Fera, Francesco ;

Condino, Francesca ;

Pugliese, Pierfrancesco ;

Lanza, Pierluigi ;

Barone, Paolo ;

Morgante, Letterio ;

Zappia, Mario ;

Aguglia, Umberto ;

Gallo, Olivier .

RADIOLOGY, 2008, 246 (01) :214-221

[9] The phenotypic spectrum of progressive supranuclear palsy [J].

Respondek, G. ;

Hoeglinger, G. U. .

PARKINSONISM & RELATED DISORDERS, 2016, 22 :S34-S36

[10] PROGRESSIVE SUPRANUCLEAR PALSY - HETEROGENEOUS DEGENERATION INVOLVING BRAIN STEM BASAL GANGLIA + CEREBELLUM WITH VERTICAL GAZE + PSEUDOBULBAR PALSY NUCHAL DYSTONIA + DEMENTIA [J].

STEELE, JC ;

OLSZEWSKI, J ;

RICHARDSON, JC .

ARCHIVES OF NEUROLOGY, 1964, 10 (04) :333-&