Synthesis of thiazolines by the reaction of aryl ketonitriles with cysteamine via microwave irradiation

被引：20

作者：

Kamila, Sukanta ^{[1
]}

Biehl, Edward R. ^{[1
]}

机构：

[1] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 02期

关键词：

D O I：

10.1002/jhet.5570440220

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thiazolines were synthesized in a one-pot reaction in excellent yield using a newly developed methodology. Ketonitriles were directly condensed with cysteamine (2-amino-thioalcohol) via microwave irradiation at 210 degrees C for 10 minutes under solvent free conditions and without my solid support. All the compounds were characterized by H-1 nmr, C-13 nmr spectroscopy and elemental analyses.

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页码：407 / 409

页数：3

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