The fine needle aspiration biopsy diagnostic criteria of proliferative breast lesions: A retrospective statistical analysis of criteria for papillomas and radial scar lesions

被引:11
作者
Field, Andrew [1 ]
Mak, Alison [1 ]
机构
[1] St Vincents Hosp, Dept Pathol Anat, Darlinghurst, NSW 2010, Australia
关键词
epithelial hyperplasia with atypia; papilloma; radial scar; stellate/meshwork fragments; papillary fragments;
D O I
10.1002/dc.20652
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
This study aimed to analyze statistically the accuracy of fine needle aspiration biopsy cytological criteria in diagnosing epithelial hyperplasia with atypia (EHA), papillary lesions (PAP), and radial scar/complex sclerosing lesions (RS/CSL). The 42 criteria studied were extracted from a literature review and those developed and used in our department. Cytological cases with diagnoses of EHA, PAP, and RS/CSL for the period of 1997-2001 were correlated with relevant histological follow-up and the positive predictive power of these diagnoses have been presented in an earlier publication. Some 77 cases with definite, specific histological diagnoses of atypia or a more severe lesion, PAP and RS/CSL, were reviewed and scored using 55 cytological criteria. As the group of EHA and RS/CSL yielded a smaller number of cases, these were grouped together in the statistical analysis and compared to PAP. The cytological features, which were most diagnostic for PAP, were stellate (Odds ratio 1.75) and meshwork (Odds ratio 3.29) tissue fragments, while the presence of tubular structures was inversely proportional to the histological outcome of PAP. True papillary fragments were uncommon and not statistically significant in diagnosing PAP of the breast. (c) 2007 Wiley-Liss. Inc.
引用
收藏
页码:386 / 397
页数:12
相关论文
共 42 条
[1]  
Abati A, 1997, DIAGN CYTOPATHOL, V16, P295
[2]   Cytological criteria for the diagnosis of intraductal hyperplasia, ductal carcinoma in situ, and invasive carcinoma of the breast [J].
Bofin, AM ;
Lydersen, S ;
Hagmar, BM .
DIAGNOSTIC CYTOPATHOLOGY, 2004, 31 (04) :207-215
[3]  
Bondeson L, 1997, DIAGN CYTOPATHOL, V17, P315, DOI 10.1002/(SICI)1097-0339(199711)17:5<315::AID-DC2>3.0.CO
[4]  
2-9
[5]  
Bonzanini M, 1997, DIAGN CYTOPATHOL, V17, P353, DOI 10.1002/(SICI)1097-0339(199711)17:5<353::AID-DC8>3.0.CO
[6]  
2-B
[7]  
Carder PJ, 2004, CYTOPATHOLOGY, V15, P336
[8]   Clinical and cytologic features of papillary neoplasms of the breast [J].
Choi, YD ;
Gong, GY ;
Kim, MJ ;
Lee, JS ;
Nam, JH ;
Juhng, SW ;
Choi, C .
ACTA CYTOLOGICA, 2006, 50 (01) :35-40
[9]  
COGHILL S, 1995, BREAST DIAGNOSTIC CY, P227
[10]  
DAWSON AE, 1994, ACTA CYTOL, V38, P23